Proof of concept: could snake venoms be a potential source of bioactive compounds for control of mould growth and mycotoxin production

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dc.contributor.authorVerheecke-Vaessen, Carol
dc.contributor.authorMonte, J.
dc.contributor.authorGarcia-Cela, Esther
dc.contributor.authorMagan, Naresh
dc.contributor.authorMedina, Angel
dc.date.accessioned2020-08-11T10:28:50Z
dc.date.available2020-08-11T10:28:50Z
dc.date.issued2020-06-05
dc.description.abstractThe objective was to screen 10 snake venoms for their efficacy to control growth and mycotoxin production by important mycotoxigenic fungi including Aspergillus flavus , Aspergillus westerdijkiae , Penicillium verrucosum , Fusarium graminearum and F. langsethiae . The Bioscreen C rapid assay system was used. The venoms from the Viperidae snake family delayed growth of some of the test fungi, especially F. graminearum and F. langsethiae and sometimes A. flavus . Some were also able to reduce mycotoxin production. The two most potent crude snake venoms (Naja nigricollis and N. siamensis; 41 and 43 fractions, respectively) were further fractionated and 83/84 of these fractions were able to reduce mycotoxin production by >90% in two of the mycotoxigenic fungi examined. This study suggests that there may be significant potential for the identification of novel fungistatic/fungicidal bioactive compounds as preservatives of raw and processed food commodities postā€harvest from such snake venoms.en_UK
dc.identifier.citationVerheeckeā€Vaessen C, Monte J, Garciaā€Cela E, et al., (2020) Proof of concept: could snake venoms be a potential source of bioactive compounds for control of mould growth and mycotoxin production. Letters in Applied Microbiology, Volume 71, November 2020, pp. 459-465en_UK
dc.identifier.issn0266-8254
dc.identifier.urihttps://doi.org/10.1111/lam.13338
dc.identifier.urihttp://dspace.lib.cranfield.ac.uk/handle/1826/15661
dc.language.isoenen_UK
dc.publisherWileyen_UK
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.titleProof of concept: could snake venoms be a potential source of bioactive compounds for control of mould growth and mycotoxin productionen_UK
dc.typeArticleen_UK

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