Proof of concept: could snake venoms be a potential source of bioactive compounds for control of mould growth and mycotoxin production

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2020-06-05

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Wiley

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Article

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0266-8254

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Verheecke‐Vaessen C, Monte J, Garcia‐Cela E, et al., (2020) Proof of concept: could snake venoms be a potential source of bioactive compounds for control of mould growth and mycotoxin production. Letters in Applied Microbiology, Volume 71, November 2020, pp. 459-465

Abstract

The objective was to screen 10 snake venoms for their efficacy to control growth and mycotoxin production by important mycotoxigenic fungi including Aspergillus flavus , Aspergillus westerdijkiae , Penicillium verrucosum , Fusarium graminearum and F. langsethiae . The Bioscreen C rapid assay system was used. The venoms from the Viperidae snake family delayed growth of some of the test fungi, especially F. graminearum and F. langsethiae and sometimes A. flavus . Some were also able to reduce mycotoxin production. The two most potent crude snake venoms (Naja nigricollis and N. siamensis; 41 and 43 fractions, respectively) were further fractionated and 83/84 of these fractions were able to reduce mycotoxin production by >90% in two of the mycotoxigenic fungi examined. This study suggests that there may be significant potential for the identification of novel fungistatic/fungicidal bioactive compounds as preservatives of raw and processed food commodities post‐harvest from such snake venoms.

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Github

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Attribution 4.0 International

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