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Browsing by Supervisor "Morgan, Sarah"

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Classification of endocrine resistant breast cancers from transcriptomic datasets using multi-gene signatures

Larionov, Alexey (Cranfield UniversityCranfield Health, 2012-09)

Breast cancer is the most frequent cancer in women in developed countries. Endocrine treatment is indicated to the majority of breast cancer patients. However, in some cases it does not work despite the current clinical ...
Development of a quantum dot-encoded microsphere suspension assay for the genotyping of single nucleotide polymorphisms

Thiollet, Sarah (Cranfield University, 2009-03)

This thesis describes the investigation of quantum dot-doped particle fluorescent technology commercially available for its application to analyte profiling in suspension. The first part of the thesis described the ...
Development of a rapid immunoassay for human pathogenic markers

Lawton, Nicola Jane (Cranfield UniversityCranfield Health, 2006-09)

A demand exists for a fast, sensitive, reliable and economical test for pyogenic sepsis that provides a “real time” bed-side assessment. Detection of significant intra-abdominal sepsis can be particularly problematic in ...
Development of new fluorescent silica and multifunctional nanoparticles for bio-imaging and diagnostics

Lemelle, Arnaud (Cranfield University, 2011-03)

Silica nanoparticles are effective fluorophore carriers with high potential in imaging, diagnostics, and therapy. The particles are resistant to drastic change of environmental conditions (pH, temperature etc. and insulate ...
Investigating the impact of NHS based ovarian cancer screening

Nicholson, S. M. (Cranfield University, 2010-02)

the UK ovarian cancer is the fifth most common cancer in females and after uterine cancer, the second most common gynaecological cancer. There were 6,596 new cases diagnosed in the UK in 2006. The majority of women who ...
Investigation of the effect of structured hyaluronic acid surfaces on cell proliferation and expression of HA cellular receptors:CD44 and RHAMM

Marques, Ana Catia Ferrao (Cranfield University, 2011-03)

Hyaluronic acid (HA) is one of the major components of the extracellular matrix; and may exhibit different biological functions, dependent on polymer molecular weight (MW). The signalling events performed by HA are mediated ...
Towards objective endoscopic diagnosis of Barrett's associated early neoplasia using fibre-optic Raman Spectroscopy

Almond, Laurence Maximilian (Cranfield University, 2012-08)

This translational research evaluates a novel, custom-built Raman probe for potential application as an in vivo diagnostic tool in the oesophagus. Raman spectroscopy (RS) is a well established analytical technique which ...

Browsing by Supervisor "Morgan, Sarah"

Browsing by Supervisor "Morgan, Sarah"

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