Abstract:
Silica nanoparticles are effective fluorophore carriers with high potential in
imaging, diagnostics, and therapy. The particles are resistant to drastic change
of environmental conditions (pH, temperature etc. and insulate the dyes so as to
protect them from photobleaching. Silica chemistry is also versatile and affords
an easy modification of the particle composition and surface to integrate
targeting ligands or to integrate other nanoparticles. Regardless of their
advantages, there exists a lack of dye diversity in the literature that is connected
to a low affinity for
potential tools for biology and medicineThis thesis describes the development
of an alternative method for the synthesis of fluorescent silica nanoparticles and
their modification to incorporate iron oxide and gold. cont/d.