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Browsing by Author "McCarthy, Ronan R."

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    Engineering biology applications for environmental solutions: potential and challenges
    (Springer Nature, 2025-04) Lea-Smith, David J.; Hassard, Francis; Coulon, Frederic; Partridge, Natalie; Horsfall, Louise; Parker, Kyle D. J.; Smith, Robert D. J.; McCarthy, Ronan R.; McKew, Boyd A.; Gutierrez, Tony; Kumar, Vinod; Dotro, Gabriella; Yang, Zhugen; Curtis, Thomas P.; Golyshin, Peter; Heaven, Sonia; Jefferson, Bruce; Jeffrey, Paul; Jones, Davey L.; Le Corre Pidou, Kristell; Liu, Yongqiang; Lyu, Tao; Smith, Cindy; Yakunin, Alexander; Zhang, Yue; Krasnogor, Natalio
    Engineering biology applies synthetic biology to address global environmental challenges like bioremediation, biosequestration, pollutant monitoring, and resource recovery. This perspective outlines innovations in engineering biology, its integration with other technologies (e.g., nanotechnology, IoT, AI), and commercial ventures leveraging these advancements. We also discuss commercialisation and scaling challenges, biosafety and biosecurity considerations including biocontainment strategies, social and political dimensions, and governance issues that must be addressed for successful real-world implementation. Finally, we highlight future perspectives and propose strategies to overcome existing hurdles, aiming to accelerate the adoption of engineering biology for environmental solutions.
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    Scaling-up engineering biology for enhanced environmental solutions
    (American Chemical Society, 2024-06-21) Hassard, Francis; Curtis, Thomas P.; Dotro, Gabriela C.; Golyshin, Peter; Gutierrez, Tony; Heaven, Sonia; Horsfall, Louise; Jefferson, Bruce; Jones, Davey L.; Krasnogor, Natalio; Kumar, Vinod; Lea-Smith, David J.; Le Corre Pidou, Kristell; Liu, Yongqiang; Lyu, Tao; McCarthy, Ronan R.; McKew, Boyd; Smith, Cindy; Yakunin, Alexander; Yang, Zhugen; Zhang, Yue; Coulon, Frederic
    Synthetic biology (SynBio) offers transformative solutions for addressing environmental challenges by engineering organisms capable of degrading pollutants, enhancing carbon sequestration, and valorizing waste (Figure 1). These innovations hold the potential to revolutionize bioremediation strategies, ecosystem restoration, and sustainable environmental management.

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