High level xylitol production by Pichia fermentans using non-detoxified xylose-rich sugarcane bagasse and olive pits hydrolysates

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dc.contributor.authorNarisetty, Vivek
dc.contributor.authorCastro, Eulogio
dc.contributor.authorDurgapal, Sumit
dc.contributor.authorCoulon, Frederic
dc.contributor.authorJacob, Samuel
dc.contributor.authorKumar, Dinesh
dc.contributor.authorAwasthi, Mukesh Kumar
dc.contributor.authorPant, Kamal Kishore
dc.contributor.authorParameswaran, Binod
dc.contributor.authorKumar, Vinod
dc.date.accessioned2021-10-05T13:10:30Z
dc.date.available2021-10-05T13:10:30Z
dc.date.issued2021-09-22
dc.description.abstractHemicellulosic sugars, the overlooked fraction of lignocellulosic residues can serve as potential and cost-effective raw material that can be exploited for xylitol production. Xylitol is a top platform chemical with applications in food and pharmaceutical industries. Sugarcane bagasse (SCB) and olive pits (OP) are the major waste streams from sugar and olive oil industries, respectively. The current study evaluated the potential of Pichia fermentans for manufacturing of xylitol from SCB and OP hydrolysates through co-fermentation strategy. The highest xylitol accumulation was noticed with a glucose and xylose ratio of 1:10 followed by feeding with xylose alone. The fed-batch cultivation using pure xylose, SCB, and OP hydrolysates, resulted in xylitol accumulation of 102.5, 86.6 and 71.9 g/L with conversion yield of 0.78, 0.75 and 0.74 g/g, respectively. The non-pathogenic behaviour and ability to accumulate high xylitol levels from agro-industrial residues demonstrates the potential of P. fermentans as microbial cell factory.en_UK
dc.identifier.citationNarisetty V, Castro E, Durgapal S, et al., (2021) High level xylitol production by Pichia fermentans using non-detoxified xylose-rich sugarcane bagasse and olive pits hydrolysates. Bioresource Technology, Volume 342, December 2021, Article number 126005en_UK
dc.identifier.issn0960-8524
dc.identifier.urihttps://doi.org/10.1016/j.biortech.2021.126005
dc.identifier.urihttp://dspace.lib.cranfield.ac.uk/handle/1826/17142
dc.language.isoenen_UK
dc.publisherElsevieren_UK
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectXyloseen_UK
dc.subjectXylitolen_UK
dc.subjectPichia fermentansen_UK
dc.subjectSugarcane bagasseen_UK
dc.subjectOlive pitsen_UK
dc.titleHigh level xylitol production by Pichia fermentans using non-detoxified xylose-rich sugarcane bagasse and olive pits hydrolysatesen_UK
dc.typeArticleen_UK

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