Salting-out assisted solvent extraction of L (+) lactic acid obtained after fermentation of sugarcane bagasse hydrolysate

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dc.contributor.authorBaral, Pratibha
dc.contributor.authorPundir, Anushka
dc.contributor.authorKurmi, Akhilesh
dc.contributor.authorSingh, Raghuvir
dc.contributor.authorKumar, Vinod
dc.contributor.authorAgrawal, Deepti
dc.date.accessioned2021-05-12T09:48:58Z
dc.date.available2021-05-12T09:48:58Z
dc.date.issued2021-04-18
dc.description.abstractLactic acid is among the twelve platform chemicals produced from inexpensive and renewable feedstocks such as lignocellulosic biomass. The present study illustrates salting-out assisted solvent extraction of L (+) lactic acid, derived from sugarcane bagasse hydrolysate. Screening studies with various extractants and diluents revealed that a combination of tri-n-butyl phosphate and ethyl acetate yielded the best results and extracted 59.63 ± 1.28% lactic acid from the dilute fermentation broth adjusted to a pH of 1.6 ± 0.2. Various inorganic salts were screened to enhance extraction efficiency further. The addition of 60% (w/v) ammonium sulfate improved the lactic acid extraction by 36.17%. This salt concentration successfully extracted 85.95 ± 0.44% lactic acid to the organic phase under optimized conditions from the fermentation broth at a pH of ~ 2.5 containing 40–100 g L−1 lactic acid. Recovery of > 80% salt is also shown using chilled acetone, which upon reuse showed a nominal decline of 3.3% during extraction. Thus an eco-friendly approach using a green solvent like ethyl acetate with mild operating conditions is demonstrated in the present study.en_UK
dc.identifier.citationBaral P, Pundi A, Kumar A, et al., (2021) Salting-out assisted solvent extraction of L (+) lactic acid obtained after fermentation of sugarcane bagasse hydrolysate. Separation and Purification Technology, Volume 269, August 2021, Article number 118788en_UK
dc.identifier.issn1383-5866
dc.identifier.urihttps://doi.org/10.1016/j.seppur.2021.118788
dc.identifier.urihttp://dspace.lib.cranfield.ac.uk/handle/1826/16670
dc.language.isoenen_UK
dc.publisherElsevieren_UK
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectLactic aciden_UK
dc.subjectSugarcane bagasse hydrolysateen_UK
dc.subjectExtractionen_UK
dc.subjectAmmonium sulphateen_UK
dc.subjectEthyl acetateen_UK
dc.subjectTri-n-butyl phosphateen_UK
dc.titleSalting-out assisted solvent extraction of L (+) lactic acid obtained after fermentation of sugarcane bagasse hydrolysateen_UK
dc.typeArticleen_UK

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