Flexible Ultrathin PolyDVB/EVB Composite Membranes for the Optimization of a Whole Blood Glucose Sensor.
| dc.contributor.author | Bridge, Kerry | - |
| dc.contributor.author | Davis, Frank | - |
| dc.contributor.author | Collyer, Stuart D. | - |
| dc.contributor.author | Higson, Seamus P. J. | - |
| dc.date.accessioned | 2011-10-11T06:59:59Z | |
| dc.date.available | 2011-10-11T06:59:59Z | |
| dc.date.issued | 2007-01-01T00:00:00Z | - |
| dc.description.abstract | An ultrathin composite membrane has been developed as the outer covering barrier in a model amperometric glucose oxidase enzyme electrode. The membrane was formed by cathodic electropolymerization of divinylbenzene/ethylvinylbenzene at the surface of a gold coated polyester support membrane. Permeability coefficients were determined for O2 and glucose across membranes with a range of polymer thicknesses. Anionic interferents (such as ascorbate), were screened from the working electrode via a charge exclusion mechanism. The enzyme electrode showed an initial 10% signal drift when first exposed to whole human blood over a period of 2 hours, after which responses remained essentially stable. Whole blood patient glucose determinations yielded a correlation coefficient of r2=0.99 compared to standard hospital analyses. | en_UK |
| dc.identifier.citation | Kerry Bridge, Frank Davis, Stuart Collyer, Séamus P. J. Higson; Flexible Ultrathin PolyDVB/EVB Composite Membranes for the Optimization of a Whole Blood Glucose Sensor. Electroanalysis, 2007, Volume 19, Issue 4 , Pages 487 - 495 | - |
| dc.identifier.issn | 1040-0397 | - |
| dc.identifier.uri | http://dx.doi.org/10.1002/elan.200603754 | - |
| dc.identifier.uri | http://dspace.lib.cranfield.ac.uk/handle/1826/2355 | |
| dc.language.iso | en_UK | - |
| dc.publisher | John Wiley & Sons, Ltd | en_UK |
| dc.subject | Cathodic electropolymerization | en_UK |
| dc.subject | Composite membrane | en_UK |
| dc.subject | Amperometric enzyme electrode | en_UK |
| dc.subject | Polydivinylbenzene | en_UK |
| dc.subject | Blood | en_UK |
| dc.title | Flexible Ultrathin PolyDVB/EVB Composite Membranes for the Optimization of a Whole Blood Glucose Sensor. | en_UK |
| dc.type | Article | - |