AuAg nanocages/graphdiyne for rapid elimination and detection of trace pathogenic bacteria

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dc.contributor.authorBai, Qiang
dc.contributor.authorLuo, Hongyang
dc.contributor.authorShi, Shugao
dc.contributor.authorLiu, Shen
dc.contributor.authorWang, Lina
dc.contributor.authorDu, Fanglin
dc.contributor.authorYang, Zhugen
dc.contributor.authorZhu, Zhiling
dc.contributor.authorSui, Ning
dc.date.accessioned2022-01-19T16:16:52Z
dc.date.available2022-01-19T16:16:52Z
dc.date.issued2022-01-10
dc.description.abstractWe prepared a biocompatible AuAg nanocages/graphdiyne @ polyethylene glycol (AuAg/GDY@PEG) composite. The combination of AuAg and GDY to obtain a synergistically enhanced photothermal effect, and the antibacterial effect of GDY and AuAg are used in combined anti-infective therapy. The in vitro antibacterial activity of AuAg/GDY@PEG was investigated, showing an impressive broad-spectrum antibacterial activity with the killing rate > 99.999%. Based on the photothermal conversion ability of AuAg/GDY@PEG, a simple photothermal immunoassay for pathogenic bacteria was successfully established. Sandwich immune response was performed on a microporous plate, the microplate containing the antibody binds specifically to the bacterium being tested, which then binds to the material with the antibody on its surface, and the signal was a change in temperature under 808 nm near-infrared light. The limit of detection (LOD) for S. typhimurium detection is 103 CFU mL−1, with a range of 103–107 CFU mL−1. This method is accurate, rapid and low-cost, which can be used for on-site detection of pathogenic bacteria in food.en_UK
dc.identifier.citationBai Q, Luo H, Shi S, et al., (2022) AuAg nanocages/graphdiyne for rapid elimination and detection of trace pathogenic bacteria. Journal of Colloid and Interface Science, Volume 613, May 2022, pp. 376-383en_UK
dc.identifier.issn0021-9797
dc.identifier.urihttps://doi.org/10.1016/j.jcis.2022.01.046
dc.identifier.urihttp://dspace.lib.cranfield.ac.uk/handle/1826/17446
dc.language.isoenen_UK
dc.publisherElsevieren_UK
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectPhotothermal effecten_UK
dc.subjectGold-silver nanocagesen_UK
dc.subjectGraphdiyneen_UK
dc.subjectImmunoassayen_UK
dc.subjectAntibacterialen_UK
dc.titleAuAg nanocages/graphdiyne for rapid elimination and detection of trace pathogenic bacteriaen_UK
dc.typeArticleen_UK

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