Visceral fat mass as a novel risk factor for predicting gestational diabetes in obese pregnant women

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dc.contributor.authorBalani, Jyoti
dc.contributor.authorHyer, S. L.
dc.contributor.authorShehata, H
dc.contributor.authorMohareb, Fady R.
dc.date.accessioned2018-03-19T18:30:13Z
dc.date.available2018-03-19T18:30:13Z
dc.date.issued2018-03-14
dc.description.abstractObjective To develop a model to predict gestational diabetes mellitus incorporating classical and a novel risk factor, visceral fat mass. Methods Three hundred two obese non-diabetic pregnant women underwent body composition analysis at booking by bioimpedance analysis. Of this cohort, 72 (24%) developed gestational diabetes mellitus. Principal component analysis was initially performed to identify possible clustering of the gestational diabetes mellitus and non-GDM groups. A machine learning algorithm was then applied to develop a GDM predictive model utilising random forest and decision tree modelling. Results The predictive model was trained on 227 samples and validated using an independent testing subset of 75 samples where the model achieved a validation prediction accuracy of 77.53%. According to the decision tree developed, visceral fat mass emerged as the most important variable in determining the risk of gestational diabetes mellitus. Conclusions We present a model incorporating visceral fat mass, which is a novel risk factor in predicting gestational diabetes mellitus in obese pregnant womenen_UK
dc.identifier.citationBalani J, Hyer SL, Shehata H, Mohareb F, Visceral fat mass as a novel risk factor for predicting gestational diabetes in obese pregnant women, Obstetric Medicine, Obstetric Medicine, Volume: 11, issue: 3, September 2018, pp121-125en_UK
dc.identifier.issn1753-495X
dc.identifier.urihttp://dx.doi.org/10.1177/1753495X17754149
dc.identifier.urihttp://dspace.lib.cranfield.ac.uk/handle/1826/13104
dc.language.isoenen_UK
dc.publisherSAGEen_UK
dc.rights© The Authors. The final, definitive version of this article has been published in the Journal: Obstetric Medicine. ©SAGE Publications Ltd, Journals Online: http://online.sagepub.com/*
dc.subjectGestational diabetesen_UK
dc.subjectObesityen_UK
dc.subjectVisceral fat massen_UK
dc.subjectPredictive modelen_UK
dc.subjectPrinciple component analysisen_UK
dc.subjectMachine learningen_UK
dc.titleVisceral fat mass as a novel risk factor for predicting gestational diabetes in obese pregnant womenen_UK
dc.typeArticleen_UK

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