Paper-based microfluidic aptasensors

dc.contributor.authorMing, Tao
dc.contributor.authorLuo, Jinping
dc.contributor.authorLiu, Juntao
dc.contributor.authorSun, Shuai
dc.contributor.authorXing, Yu
dc.contributor.authorWang, Hao
dc.contributor.authorXiao, Guihua
dc.contributor.authorDeng, Yu
dc.contributor.authorCheng, Yan
dc.contributor.authorYang, Zhugen
dc.contributor.authorJin, Hongyan
dc.contributor.authorCai, Xinxia
dc.date.accessioned2020-10-19T16:31:13Z
dc.date.available2020-10-19T16:31:13Z
dc.date.issued2020-10-04
dc.description.abstractFor in-situ disease markers detection, point-of-care (POC) diagnosis has great advantages in speed and cost compared with traditional techniques. The rapid diagnosis, prognosis, and surveillance of diseases can significantly reduce disease-related mortality and trauma. Therefore, increasing attention has been paid to the POC diagnosis devices due to their excellent diagnosis speed and portability. Over the past ten years, paper-based microfluidic aptasensors have emerged as a class of critical POC diagnosis devices and various aptasensors have been proposed to detect various disease markers. However, most aptasensors need further improvement before they can actually enter the market and be widely used. There is thus an urgent need to sort out the key points of preparing the aptasensors and the direction that needs to be invested in. This review summarizes the representative articles in the development of paper-based microfluidic aptasensors. These works can be divided into paper-based optical aptasensors and paper-based electrochemical aptasensors according to their output signals. Significant focus is applied to these works according to the following three parts: (1) The ingenious design of device structure; (2) Application and synthesis of nanomaterial; (3) The detection principle of the proposed aptasensor. This is a detailed and comprehensive review of paper-based microfluidic aptasensors. The accomplishments and shortcomings of the current aptasensors are outlined, the development direction and the future prospective are given. It is hoped that the research in this review can provide a reference for further development of more advanced, more effective paper-based microfluidic aptasensors for POC disease markers diagnosisen_UK
dc.identifier.citationMing T, Luo J, Liu J, et al., (2020) Paper-based microfluidic aptasensors. Biosensors and Bioelectronics, Volume 170, December 2020, Article number 112649en_UK
dc.identifier.issn0956-5663
dc.identifier.urihttps://doi.org/10.1016/j.bios.2020.112649
dc.identifier.urihttp://dspace.lib.cranfield.ac.uk/handle/1826/15903
dc.language.isoenen_UK
dc.publisherElsevieren_UK
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectPoint-of-care Diagnosisen_UK
dc.subjectNanomaterialen_UK
dc.subjectPortable equipmenten_UK
dc.subjectPoint-of-care Diagnosisen_UK
dc.subjectMicrofluidic chipen_UK
dc.subjectPaper-based deviceen_UK
dc.subjectAptasensoren_UK
dc.titlePaper-based microfluidic aptasensorsen_UK
dc.typeArticleen_UK

Files

Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Paper-based microfluidic aptasensors-2020.pdf
Size:
1.59 MB
Format:
Adobe Portable Document Format
Description:
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.63 KB
Format:
Item-specific license agreed upon to submission
Description: