Development of the custom polymeric materials specific for aflatoxin B1 and ochratoxin A for application with the ToxiQuant T1 sensor tool
Date
2010-04-16T00:00:00Z
Supervisor/s
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier Science B.V., Amsterdam.
Department
Type
Article
ISSN
0021-9673
Format
Free to read from
Citation
Elena Piletska, Kal Karim, Raymond Coker, Sergey Piletsky, Development of the
custom polymeric materials specific for aflatoxin B1 and ochratoxin A for
application with the ToxiQuant T1 sensor tool, Journal of Chromatography A,
Volume 1217, Issue 16, Extraction Techniques, 16 April 2010, Pages 2543-2547
Abstract
Two polymers were computationally designed with affinity to two of the most abundant mycotoxins aflatoxin B1 (AFB1) and ochratoxin A (OTA) for application in the ToxiQuant T1 System. The principle of quantification of AFB1 and OTA using the ToxiQuant T1 instrument comprised of a fluorimetric analysis of mycotoxins adsorbed on the polymer upon exposure to UV light. High affinity of the developed resins allowed the adsorption of both toxins as discrete bands on the top of the cartridge with detection limit as low as 1 ng quantity of mycotoxins.
Description
Software Description
Software Language
Github
Keywords
Mycotoxins, Aflatoxin B1, Ochratoxin A, Computational modelling, Solid-phase extraction