A compactness based saliency approach for leakages detection in fluorescein angiogram

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dc.contributor.authorZhao, Yitian
dc.contributor.authorSu, Pan
dc.contributor.authorYang, Jian
dc.contributor.authorZhao, Yifan
dc.contributor.authorZheng, Yalin
dc.contributor.authorWang, Yongtian
dc.date.accessioned2016-08-15T13:32:04Z
dc.date.available2016-08-15T13:32:04Z
dc.date.issued2016-07-26
dc.description.abstractThis study has developed a novel saliency detection method based on compactness feature for detecting three common types of leakage in retinal fluorescein angiogram: large focal, punctate focal, and vessel segment leakage. Leakage from retinal vessels occurs in a wide range of retinal diseases, such as diabetic maculopathy and paediatric malarial retinopathy. The proposed framework consists of three major steps: saliency detection, saliency refinement and leakage detection. First, the Retinex theory is adapted to address the illumination inhomogeneity problem. Then two saliency cues, intensity and compactness, are proposed for the estimation of the saliency map of each individual superpixel at each level. The saliency maps at different levels over the same cues are fused using an averaging operator. Finally, the leaking sites can be detected by masking the vessel and optic disc regions. The effectiveness of this framework has been evaluated by applying it to different types of leakage images with cerebral malaria. The sensitivity in detecting large focal, punctate focal and vessel segment leakage is 98.1, 88.2 and 82.7 %, respectively, when compared to a reference standard of manual annotations by expert human observers. The developed framework will become a new powerful tool for studying retinal conditions involving retinal leakage.en_UK
dc.identifier.citationZhao Y, Su P, Yang J, Zhao Y, Zheng Y, Wang Y, A compactness based saliency approach for leakages detection in fluorescein angiogram, International Journal of Machine Learning and Cybernetics, Vol. 8, Issue 6, December 2017, pp. 1971-1979en_UK
dc.identifier.issn1868-8071
dc.identifier.urihttp://dx.doi.org/10.1007/s13042-016-0573-4
dc.identifier.urihttps://dspace.lib.cranfield.ac.uk/handle/1826/10300
dc.language.isoenen_UK
dc.publisherSpringer Verlagen_UK
dc.rightsAttribution-NonCommercial 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.subjectSaliencyen_UK
dc.subjectCompactnessen_UK
dc.subjectLeakageen_UK
dc.subjectFluorescein angiographyen_UK
dc.subjectMalarial retinopathyen_UK
dc.titleA compactness based saliency approach for leakages detection in fluorescein angiogramen_UK
dc.typeArticleen_UK

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