Surface plasmon resonance imaging for affinity-based biosensors

dc.contributor.authorScarano, Simona
dc.contributor.authorMascini, Marco
dc.contributor.authorTurner, Anthony P. F.
dc.contributor.authorMinunni, Maria E.
dc.date.accessioned2010-01-06T13:23:21Z
dc.date.available2010-01-06T13:23:21Z
dc.date.issued2010-01-15
dc.description.abstractSPR imaging (SPRi) is at the forefront of optical label-free and real-time detection. It offers the possibility of monitoring hundreds of biological interactions simultaneously and from the binding profiles, allows the estimation of the kinetic parameters of the interactions between the immobilised probes and the ligands in solution. We review the current state of development of SPRi technology and its application including commercially available SPRi instruments. Attention is also given to surface chemistries for biochip functionalisation and suitable approaches to improve sensitivity.en_UK
dc.identifier.citationSimona Scarano, Marco Mascini, Anthony P.F. Turner, Maria Minunni, Surface plasmon resonance imaging for affinity-based biosensors, Biosensors and Bioelectronics, Volume 25, Issue 5, 15 January 2010, Pages 957-966en_UK
dc.identifier.issn0956-5663
dc.identifier.urihttp://dx.doi.org/10.1016/j.bios.2009.08.039
dc.identifier.urihttp://hdl.handle.net/1826/4104
dc.language.isoenen_UK
dc.publisherElsevieren_UK
dc.subjectSurface plasmon resonance imagingen_UK
dc.subjectSPRien_UK
dc.subjectAffinity sensingen_UK
dc.subjectImmobilisation chemistryen_UK
dc.subjectSignal amplification immunosensoren_UK
dc.subjectAptasensoren_UK
dc.subjectOptical sensoren_UK
dc.titleSurface plasmon resonance imaging for affinity-based biosensorsen_UK
dc.typeArticleen_UK

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