Printable biosensors towards next-generation point-of-care testing: paper substrate as an example

dc.contributor.authorLiu, Yaolin
dc.contributor.authorLu, Sheng
dc.contributor.authorZhang, Zhiheng
dc.contributor.authorYang, Zhugen
dc.contributor.authorCui, Xiaolin
dc.contributor.authorLiu, Guozhen
dc.date.accessioned2023-07-05T13:42:27Z
dc.date.available2023-07-05T13:42:27Z
dc.date.issued2023-06-26
dc.description.abstractPrintable biosensors have gained numerous exciting advancements towards downstream applications in fundamental biomedical research, healthcare, food safety, environmental monitoring and governance, and to name a few. Particularly, paper-based printable biosensors have gained rising popularity in providing affordable platforms due to their merits, such as cost-effective, accurate, simple, and efficient detection of diseases for clinical diagnosis. In addition to advantages and opportunities in point-of-care detection, printable biosensors are also facing challenges. Herein, this review aims to provide a systematic summary of the development of printable biosensors, with a special focus on paper-based printable biosensors. Different types of substrates for printable biosensors are highlighted first. Then we mainly focus on paper substrates with superior properties like low-cost, simple, flexible, lightweight, recyclable, etc. In addition, current printing technologies to fabricate paper-based sensors, including wax printing, photolithography, screen printing, inkjet printing, and laser printing summarize, are discussed, together with strategies for biomolecular fabrication on substrates and transducers. Finally, we also discuss the challenges and possible future perspectives, hoping to provide researchers and clinicians with informative insights into paper-based printable biosensors for a smart and effective point-of-care purpose.en_UK
dc.identifier.citationLiu Y, Lu S, Zhang Z, et al., (2023) Printable biosensors towards next-generation point-of-care testing: paper substrate as an example. Lab on a Chip, Volume 23, Issue 15, August 2023, pp. 3328-3352en_UK
dc.identifier.issn1473-0197
dc.identifier.urihttps://doi.org/10.1039/D3LC00038A
dc.identifier.urihttps://dspace.lib.cranfield.ac.uk/handle/1826/19932
dc.language.isoenen_UK
dc.publisherRoyal Society of Chemistryen_UK
dc.rightsAttribution-NonCommercial 3.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/*
dc.subjectPrintable biosensorsen_UK
dc.subjectpoint-of-care testingen_UK
dc.subjectmicrofluidic paper-based analytical devicesen_UK
dc.subjectchallengesen_UK
dc.titlePrintable biosensors towards next-generation point-of-care testing: paper substrate as an exampleen_UK
dc.typeArticleen_UK

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