Advances in molecular and genomic research to safeguard food and feed supply from aflatoxin contamination

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dc.contributor.authorBhatnagar, D
dc.contributor.authorRajasekaran, K
dc.contributor.authorGilbert, M
dc.contributor.authorCary, J. W.
dc.contributor.authorMagan, Naresh
dc.date.accessioned2018-03-13T11:18:34Z
dc.date.available2018-03-13T11:18:34Z
dc.date.issued2018-02-23
dc.description.abstractWorldwide recognition that aflatoxin contamination of agricultural commodities by the fungus Aspergillus flavus is a global problem has significantly benefitted from global collaboration for understanding the contaminating fungus, as well as for developing and implementing solutions against the contamination. The effort to address this serious food and feed safety issue has led to a detailed understanding of the taxonomy, ecology, physiology, genomics and evolution of A. flavus, as well as strategies to reduce or control pre-harvest aflatoxin contamination, including (1) biological control, using atoxigenic aspergilli, (2) proteomic and genomic analyses for identifying resistance factors in maize as potential breeding markers to enable development of resistant maize lines, and (3) enhancing host-resistance by bioengineering of susceptible crops, such as cotton, maize, peanut and tree nuts. A post-harvest measure to prevent the occurrence of aflatoxin contamination in storage is also an important component for reducing exposure of populations worldwide to aflatoxins in food and feed supplies. The effect of environmental changes on aflatoxin contamination levels has recently become an important aspect for study to anticipate future contamination levels. The ability of A. flavus to produce dozens of secondary metabolites, in addition to aflatoxins, has created a new avenue of research for understanding the role these metabolites play in the survival and biodiversity of this fungus. The understanding of A. flavus, the aflatoxin contamination problem, and control measures to prevent the contamination has become a unique example for an integrated approach to safeguard global food and feed safety.en_UK
dc.identifier.citationBhatnagar D, Rajasekaran K, Gilbert M, Cary JW, Magan N, Advances in molecular and genomic research to safeguard food and feed supply from aflatoxin contamination, Vol. 11, Issue 1, 2018, pp. 47-72en_UK
dc.identifier.issn1875-0710
dc.identifier.urihttp://dx.doi.org/10.3920/WMJ2017.2283
dc.identifier.urihttp://dspace.lib.cranfield.ac.uk/handle/1826/13079
dc.language.isoenen_UK
dc.publisherWageningen Academic Publishersen_UK
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subjectAspergillus flavusen_UK
dc.subjectSecondary metabolitesen_UK
dc.subjectPreharvest controlen_UK
dc.subjectPostharvest controlen_UK
dc.subjectAflatoxinen_UK
dc.titleAdvances in molecular and genomic research to safeguard food and feed supply from aflatoxin contaminationen_UK
dc.typeArticleen_UK

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