Process optimisation for production and recovery of succinic acid using xylose-rich hydrolysates by Actinobacillus succinogenes

Simple item page
dc.contributor.authorJokodola, Esther Oreoluwa
dc.contributor.authorNarisetty, Vivek
dc.contributor.authorCastro, Eulogio
dc.contributor.authorDurgapal, Sumit
dc.contributor.authorCoulon, Frederic
dc.contributor.authorSindhu, Raveendran
dc.contributor.authorBinod, Parameswaran
dc.contributor.authorBanu, J. Rajesh
dc.contributor.authorKumar, Gopalakrishnan
dc.contributor.authorKumar, Vinod
dc.date.accessioned2021-11-16T16:42:46Z
dc.date.available2021-11-16T16:42:46Z
dc.date.issued2021-10-28
dc.description.abstractSuccinic acid (SA) is a top platform chemical obtainable from biomass. The current study evaluated the potential of Actinobacillus succinogenes for SA production using xylose-rich hemicellulosic fractions of two important lignocellulosic feedstocks, olive pits (OP) and sugarcane bagasse (SCB) and the results were compared with pure xylose. Initial experiments were conducted in shake flask followed by batch and fed-batch cultivation in bioreactor. Further separation of SA from the fermented broth was carried out by adapting direct crystallisation method. During fed-batch culture, maximum SA titers of 36.7, 33.6, and 28.7 g/L was achieved on pure xylose, OP and SCB hydrolysates, respectively, with same conversion yield of 0.27 g/g. The recovery yield of SA accumulated on pure xylose, OP and SCB hydrolysates was 79.1, 76.5, and 75.2%, respectively. The results obtained are of substantial value and pave the way for development of sustainable SA biomanufacturing in an integrated biorefinery.en_UK
dc.identifier.citationJokodola EO, Narisetty V, Castro E, et al., (2022) Process optimisation for production and recovery of succinic acid using xylose-rich hydrolysates by Actinobacillus succinogenes. Bioresource Technology, Volume 344, Part B, January 2022, Article number 126224en_UK
dc.identifier.issn0960-8524
dc.identifier.urihttps://doi.org/10.1016/j.biortech.2021.126224
dc.identifier.urihttp://dspace.lib.cranfield.ac.uk/handle/1826/17273
dc.language.isoenen_UK
dc.publisherElsevieren_UK
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectSuccinic aciden_UK
dc.subjectActinobacillus succinogenesen_UK
dc.subjectOlive pitsen_UK
dc.subjectSugarcane bagasseen_UK
dc.subjectPure xyloseen_UK
dc.subjectDownstream processingen_UK
dc.titleProcess optimisation for production and recovery of succinic acid using xylose-rich hydrolysates by Actinobacillus succinogenesen_UK
dc.typeArticleen_UK

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
production_and_recovery_of_succinic_acid-2021.pdf
Size:
1.04 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.63 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Staff publications (SWEE)