Improved estimates of 222 nm far-UVC susceptibility for aerosolized human coronavirus via a validated high-fidelity coupled radiation-CFD code

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dc.contributor.authorBuchan, Andrew G.
dc.contributor.authorYang, Liang
dc.contributor.authorWelch, David
dc.contributor.authorBrenner, David J.
dc.contributor.authorAtkinson, Kirk D.
dc.date.accessioned2021-10-15T13:25:57Z
dc.date.available2021-10-15T13:25:57Z
dc.date.issued2021-10-07
dc.description.abstractTransmission of SARS-CoV-2 by aerosols has played a significant role in the rapid spread of COVID-19 across the globe. Indoor environments with inadequate ventilation pose a serious infection risk. Whilst vaccines suppress transmission, they are not 100% effective and the risk from variants and new viruses always remains. Consequently, many efforts have focused on ways to disinfect air. One such method involves use of minimally hazardous 222 nm far-UVC light. Whilst a small number of controlled experimental studies have been conducted, determining the efficacy of this approach is difficult because chamber or room geometry, and the air flow within them, influences both far-UVC illumination and aerosol dwell times. Fortunately, computational multiphysics modelling allows the inadequacy of dose-averaged assessment of viral inactivation to be overcome in these complex situations. This article presents the first validation of the WYVERN radiation-CFD code for far-UVC air-disinfection against survival fraction measurements, and the first measurement-informed modelling approach to estimating far-UVC susceptibility of viruses in air. As well as demonstrating the reliability of the code, at circa 70% higher, our findings indicate that aerosolized human coronaviruses are significantly more susceptible to far-UVC than previously thought.en_UK
dc.identifier.citationBuchan AG, Yang L, Welch D, et al., (2021) Improved estimates of 222 nm far-UVC susceptibility for aerosolized human coronavirus via a validated high-fidelity coupled radiation-CFD code. Scientific Reports, Volume 11, Article number 19930en_UK
dc.identifier.issn2045-2322
dc.identifier.urihttps://doi.org/10.1038/s41598-021-99204-0
dc.identifier.urihttp://dspace.lib.cranfield.ac.uk/handle/1826/17172
dc.language.isoenen_UK
dc.publisherNature Publishing Groupen_UK
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectMathematics and computingen_UK
dc.subjectSARS-CoV-2en_UK
dc.subjectViral infectionen_UK
dc.titleImproved estimates of 222 nm far-UVC susceptibility for aerosolized human coronavirus via a validated high-fidelity coupled radiation-CFD codeen_UK
dc.typeArticleen_UK

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