Histomorphometric analysis of the variability of the human skeleton: forensic implications

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dc.contributor.authorCummaudo, Marco
dc.contributor.authorRaffone, Caterina
dc.contributor.authorCappella, Annalisa
dc.contributor.authorMárquez-Grant, Nicholas
dc.contributor.authorCattaneo, Cristina
dc.date.accessioned2020-06-09T13:58:39Z
dc.date.available2020-06-09T13:58:39Z
dc.date.issued2020-04-23
dc.description.abstractIn the last decades, the histomorphometric analysis of bone tissue has been utilized to develop equations for species discrimination of fragmentary bone. Although this technique showed promising results, its main limitation concerns the lack of knowledge on the histomorphometric variability which may exist between different bones of the skeleton. In a previous study, we demonstrated a significant histomorphological variability in different bones of the same individual and even in different sections of the same bone. The present study aimed at investigating the extent of intra-individual variability in bone histomorphometry throughout the human adult skeleton and areas of a single bone. Samples were taken along an entire medieval male adult human skeleton (aged between 26 and 45 years), including long, flat, irregular and sesamoid bones for a total of 49 cross-sections. The histomorphometric analysis revealed that the size of both Haversian systems and Haversian canals were statistically significantly larger in long and irregular bones compared to flat bones. Moreover, osteons were generally bigger in the diaphysis compared to the proximal and distal metaphyses, whereas Haversian canals showed a higher uniformity in the different portions of each bone. The present study has highlighted the importance of conducting similar studies on both human and nonhuman skeletons at different stages of skeletal maturity in order to shed light on the extent of variability in the size of osteons and Haversian canals. This, in fact, represents an important prerequisite to develop reliable histological methods for species discrimination of fragmented bone.en_UK
dc.identifier.citationCummaudo M, Raffone C, Cappella A, et al., (2020) Histomorphometric analysis of the variability of the human skeleton: forensic implications. Legal Medicine, Volume 45, July 2020, Article number 101711en_UK
dc.identifier.issn1344-6223
dc.identifier.urihttps://doi.org/10.1016/j.legalmed.2020.101711
dc.identifier.urihttp://dspace.lib.cranfield.ac.uk/handle/1826/15485
dc.language.isoenen_UK
dc.publisherElsevieren_UK
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectBone histologyen_UK
dc.subjectHistomorphometric variabilityen_UK
dc.subjectHaversian systemen_UK
dc.subjectHaversian canalen_UK
dc.subjectHuman skeletonen_UK
dc.subjectForensic anthropologyen_UK
dc.titleHistomorphometric analysis of the variability of the human skeleton: forensic implicationsen_UK
dc.typeArticleen_UK

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