Emerging trends in high-solids enzymatic saccharification of lignocellulosic feedstocks for developing an efficient and industrially deployable sugar platform

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dc.contributor.authorBaral, Pratibha
dc.contributor.authorKumar, Vinod
dc.contributor.authorAgrawal, Deepti
dc.date.accessioned2021-10-08T15:11:56Z
dc.date.available2021-10-08T15:11:56Z
dc.date.issued2021-09-16
dc.description.abstractFor the techno-commercial success of any lignocellulosic biorefinery, the cost-effective production of fermentable sugars for the manufacturing of bio-based products is indispensable. High-solids enzymatic saccharification (HSES) is a straightforward approach to develop an industrially deployable sugar platform. Economic incentives such as reduced capital and operational expenditure along with environmental benefits in the form of reduced effluent discharge makes this strategy more lucrative for exploitation. However, HSES suffers from the drawback of non-linear and disproportionate sugar yields with increased substrate loadings. To overcome this bottleneck, researchers tend to perform HSES at high enzyme loadings. Nonetheless, the production costs of cellulases are one of the key contributors that impair the entire process economics. This review highlights the relentless efforts made globally to attain a high-titer of sugars and their fermentation products by performing efficient HSES at low cellulase loadings. In this context, technical innovations such as advancements in new pretreatment strategies, next-generation cellulase cocktails, additives, accessory enzymes, novel reactor concepts and enzyme recycling studies are especially showcased. This review further covers new insights, learnings and prospects in the area of lignocellulosic bioprocessing.en_UK
dc.identifier.citationBaral P, Kumar V, Agrawal D. (2021) Emerging trends in high-solids enzymatic saccharification of lignocellulosic feedstocks for developing an efficient and industrially deployable sugar platform. Critical Reviews in Biotechnology, Volume 42, Issue 6, 2022, pp. 873-891en_UK
dc.identifier.issn0738-8551
dc.identifier.urihttps://doi.org/10.1080/07388551.2021.1973363
dc.identifier.urihttp://dspace.lib.cranfield.ac.uk/handle/1826/17156
dc.language.isoenen_UK
dc.publisherTaylor and Francisen_UK
dc.rightsAttribution-NonCommercial 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectLignocellulosic biomassen_UK
dc.subjectcellulasesen_UK
dc.subjecthigh-solids enzymatic saccharificationen_UK
dc.subjectfermentable sugarsen_UK
dc.subjectbio-based productsen_UK
dc.titleEmerging trends in high-solids enzymatic saccharification of lignocellulosic feedstocks for developing an efficient and industrially deployable sugar platformen_UK
dc.typeArticleen_UK

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