Synthesis and characterization of jellified composites form bovine bone-derived hydroxyapatite and starch as precursors for robocasting

Date

2018-01-31

Supervisor/s

Journal Title

Journal ISSN

Volume Title

Publisher

American Chemical Society

Department

Type

Article

ISSN

2470-1343

Format

Free to read from

Citation

Miculescu F, Maidaniuc A, Miculescu M, Dan Batalu N, Cătălin Ciocoiu R, Voicu SI, Stan GE, Thakur VK, Synthesis and characterization of jellified composites from bovine bone derived hydroxyapatite and starch as precursors for robocasting, ACS Omega, Vol. 3, Issue 1, 2018, pp.1338-1349

Abstract

Hydroxyapatite–starch composites solidify rapidly via jellification, making them suitable candidates for robocasting. However, many aspects related to hydroxyapatite powder characteristics, hydroxyapatite–starch interaction, and composites composition and properties need to be aligned with robocasting requirements to achieve a notable improvement in the functionality of printed scaffolds intended for bone regeneration. This article presents a preliminary evaluation of hydroxyapatite–starch microcomposites. Thermal analysis of the starting powders was performed for predicting composites’ behavior during heat-induced densification. Also, morphology, mechanical properties, and hydroxyapatite–starch interaction were evaluated for the jellified composites and the porous bodies obtained after conventional sintering, for different starch additions, and for ceramic particle size distributions. The results indicate that starch could be used for hydroxyapatite consolidation in limited quantities, whereas the composites shall be processed under controlled temperature. Due to a different mechanical behavior induced by particle size and geometry, a wide particle size distribution of hydroxyapatite powder is recommended for further robocasting ink development.

Description

Software Description

Software Language

Github

Keywords

Casting process, Catalysts, Composites, Distribution function, Granular materials, Nanoclusters, Phase, Phase transition, Thin films, Tissue engineering

DOI

Rights

Attribution-NonCommercial 4.0 International

Relationships

Relationships

Supplements

Funder/s