Breast calcification micromorphology classification

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dc.contributor.authorRobert Scott, Robert Scott
dc.contributor.authorIain Lyburn, Iain Lyburn
dc.contributor.authorCornford, Eleanor
dc.contributor.authorBouzy, Pascaline
dc.contributor.authorStone, Nicholas
dc.contributor.authorGreenwood, Charlene
dc.contributor.authorBouybayoune, Ihsanne
dc.contributor.authorPinder, Sarah
dc.contributor.authorRogers, Keith
dc.date.accessioned2022-08-11T10:05:39Z
dc.date.available2022-08-11T10:05:39Z
dc.date.issued2022-07-25
dc.description.abstractObjectives: The importance of consistent terminology in describing the appearance of breast calcifications in mammography is well recognised. Imaging of calcifications using electron microscopy is a globally growing field of research. We therefore suggest that the time is ripe to develop a lexicon of terms for classifying the micromorphology of breast calcifications. Methods: Calcifications within a wide range of histological sections of breast tissue, both benign and malignant, were imaged by Scanning Electron Microscopy (SEM). These images were examined, and the micromorphology of calcifications present was grouped to create a classification system. Results: Based on the appearance of the calcifications observed, we propose five main categories for classification of the micromorphology of breast calcifications, namely Dense Homogenous, Punctulate, Banded, Spongy, and Aggregate. Conclusions: Use of the descriptive categories outlined here will help to ensure consistency and comparability of published observations on the micromorphology of breast calcifications. Advances in knowledge: This is the first time a lexicon and classification system has been proposed for the micromorphology of breast calcifications, as observed by scanning electron microscopy of histological sections. This will facilitate comparability of observed relationships between micromorphology, mammographic appearance, chemistry, and pathology.en_UK
dc.identifier.citationScott R, Lyburn I, Cornford E, et al., (2022) Breast calcification micromorphology classification. British Journal of Radiology, Volume 95, July 2022, Article number 20220485en_UK
dc.identifier.issn0007-1285
dc.identifier.urihttps://doi.org/10.1259/bjr.20220485
dc.identifier.urihttps://dspace.lib.cranfield.ac.uk/handle/1826/18307
dc.language.isoenen_UK
dc.publisherBritish Institute of Radiologyen_UK
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.titleBreast calcification micromorphology classificationen_UK
dc.typeArticleen_UK

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