An eclectic review on dicarboxylic acid production through yeast cell factories and its industrial prominence

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dc.contributor.authorKayalvizhi, Ramalingam
dc.contributor.authorSanjana, Jayacumar
dc.contributor.authorJacob, Samuel
dc.contributor.authorKumar, Vinod
dc.date.accessioned2024-04-26T12:36:06Z
dc.date.available2024-04-26T12:36:06Z
dc.date.issued2024-04-20
dc.description.abstractDicarboxylic acid (DCA) is a multifaceted chemical intermediate, recoursed to produce many industrially important products such as adhesives, plasticizers, lubricants, polymers, etc. To bypass the shortcomings of the chemical methods of synthesis of DCA and to reduce fossil fuel footprints, bio-based synthesis is gaining attention. In pursuit of an eco-friendly sustainable alternative method of DCA production, microbial cell factories, and renewable organic resources are gaining popularity. Among the plethora of microbial communities, yeast is being favored industrially compared to bacterial fermentation due to its hyperosmotic and low pH tolerance and flexibility for gene manipulations. By application of rapidly evolving genetic manipulation techniques, the bio-based DCA production could be made more precise and economical. To bridge the gap between supply and demand of DCA, many strategies are employed to improve the fermentation. This review briefly outlines the advancements in DCA production using yeast cell factories with the exemplification of strain improvement strategies.en_UK
dc.identifier.citationKayalvizhi R, Sanjana J, Jacob S, Kumar V. (2024) An eclectic review on dicarboxylic acid production through yeast cell factories and Its industrial prominence. Current Microbiology, Volume 81, April 2024, Article number 147en_UK
dc.identifier.eissn1432-0991
dc.identifier.issn0343-8651
dc.identifier.urihttps://doi.org/10.1007/s00284-024-03654-4
dc.identifier.urihttps://dspace.lib.cranfield.ac.uk/handle/1826/21277
dc.language.isoen_UKen_UK
dc.publisherSpringeren_UK
dc.subjectBioproductionen_UK
dc.subjectDicarboxylic aciden_UK
dc.subjectGenetic manipulationen_UK
dc.subjectGreen manufacturingen_UK
dc.subjectYeast cell factoriesen_UK
dc.titleAn eclectic review on dicarboxylic acid production through yeast cell factories and its industrial prominenceen_UK
dc.typeArticleen_UK
dcterms.dateAccepted2024-02-29

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