Characterization and modelling the mechanical behaviour of poly(l-lactic acid) for the manufacture of bioresorbable vascular scaffolds by stretch blow moulding

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dc.contributor.authorWei, Huidong
dc.contributor.authorYan, Shiyong
dc.contributor.authorGoel, Saurav
dc.contributor.authorMenary, Gary
dc.date.accessioned2019-05-08T10:24:40Z
dc.date.available2019-05-08T10:24:40Z
dc.date.issued2019-01-10
dc.description.abstractBioresorbable Vascular Scaffolds (BVS) manufactured from poly (l-lactic acid) (PLLA) offer an alternative to metal scaffolds for the treatment of coronary heart disease. One of the key steps in the manufacture of these scaffolds is the stretch blow moulding process where the PLLA is biaxially stretched above glass transition temperature (Tg), inducing biaxial orientation and thus increasing ductility, strength and stiffness. To optimise the manufacture and performance of these scaffolds it is important to understand the influence of temperature and strain rate on the constitutive behaviour of PLLA in the blow moulding process. Experiments have been performed on samples of PLLA on a custom built biaxial stretch testing machine to replicate conditions typically experienced during blow moulding i.e. in a temperature range from 70 °C to 100 °C and at strain rates of 1 s−1, 4 s−1 and 16 s−1 respectively. The data is subsequently used to calibrate a nonlinear viscoelastic material model to represent the deformation behaviour of PLLA in the blow moulding process. The results highlight the significance of temperature and strain rate on the yielding and strain hardening behaviour of PLLA and the ability of the selected model to capture it.en_UK
dc.identifier.citationWei H, Yan S, Goel S, Menary G. (2020) Characterization and modelling the mechanical behaviour of poly(l-lactic acid) for the manufacture of bioresorbable vascular scaffolds by stretch blow moulding. International Journal of Material Forming, Volume 13, January 2020, pp. 43-57en_UK
dc.identifier.issn1960-6206
dc.identifier.urihttps://doi.org/10.1007/s12289-018-01463-2
dc.identifier.urihttps://dspace.lib.cranfield.ac.uk/handle/1826/14138
dc.language.isoenen_UK
dc.publisherSpringeren_UK
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectMechanical behaviouren_UK
dc.subjectConstitutive modelen_UK
dc.subjectPLLAen_UK
dc.subjectGlass transitionen_UK
dc.subjectStretch blow mouldingen_UK
dc.titleCharacterization and modelling the mechanical behaviour of poly(l-lactic acid) for the manufacture of bioresorbable vascular scaffolds by stretch blow mouldingen_UK
dc.typeArticleen_UK

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