Analysis of MRSA Staphylococcal Chromosome cassette mecA status from next generation sequence data
| dc.contributor.advisor | Larcombe, Lee D | |
| dc.contributor.advisor | Clark, Taane | |
| dc.contributor.advisor | Bessant, Conrad | |
| dc.contributor.author | Goulden, Matthew G | |
| dc.date.accessioned | 2024-03-13T14:36:42Z | |
| dc.date.available | 2024-03-13T14:36:42Z | |
| dc.date.issued | 2012-03 | |
| dc.description.abstract | NGS sequencing libraries prepared on an Illumina NGS platform for 10 isolates of Staphylococcus aureus were analysed. After extensive pre-processing to address library quality issues, for each isolate the status of the Staphylococcal Chromosome Cassette, and its mecA gene specifying resistance to meticillin, was determined. All mecA-positive isolates encoded canonical mecA. None encoded the new variant mecA identified in strain LGA251. | en_UK |
| dc.description.coursename | Applied Bioinformatics | en_UK |
| dc.description.sponsorship | Biotechnology and Biological (BBSRC) | en_UK |
| dc.identifier.uri | https://dspace.lib.cranfield.ac.uk/handle/1826/20976 | |
| dc.language.iso | en | en_UK |
| dc.publisher | Cranfield University | en_UK |
| dc.publisher.department | SAS | en_UK |
| dc.subject | core genome | en_UK |
| dc.subject | accessory genome | en_UK |
| dc.subject | NGS sequencing libraries | en_UK |
| dc.subject | drug resistance | en_UK |
| dc.title | Analysis of MRSA Staphylococcal Chromosome cassette mecA status from next generation sequence data | en_UK |
| dc.type | Thesis or dissertation | en_UK |
| dc.type.qualificationlevel | Masters | en_UK |
| dc.type.qualificationname | MSc | en_UK |