Analysis of skin tissues spatial fluorescence distribution by the Monte Carlo simulation
Date
2003-07-21T00:00:00Z
Supervisor/s
Journal Title
Journal ISSN
Volume Title
Publisher
Iop Publishing Ltd
Department
Type
Article
ISSN
0022-3727
Format
Free to read from
Citation
D Y Churmakov, I V Meglinski, S A Piletsky and D A Greenhalgh. Influence of refractive index matching on the photon diffuse reflectance. Journal of Physics D: Applied Physics, Vol 36. No 14. (2003) 1722-1728
Abstract
A novel Monte Carlo technique of simulation of spatial fluorescence distribution within the human skin is presented. The computational model of skin takes into account the spatial distribution of fluorophores, which would arise due to the structure of collagen fibres, compared to the epidermis and stratum corneum where the distribution of fluorophores is assumed to be homogeneous. The results of simulation suggest that distribution of auto-fluorescence is significantly suppressed in the near-infrared spectral region, whereas the spatial distribution of fluorescence sources within a sensor layer embedded in the epidermis is localized at an ‘effective’ de