Catalytic molecularly imprinted polymer membranes: Development of the biomimetic sensor for phenols detection

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dc.contributor.authorSergeyeva, T. A.-
dc.contributor.authorSlinchenko, O. A.-
dc.contributor.authorGorbach, L. A.-
dc.contributor.authorMatyushov, V. F.-
dc.contributor.authorBrovko, O. O.-
dc.contributor.authorPiletsky, Sergey A.-
dc.contributor.authorSergeeva, L. M.-
dc.contributor.authorElska, G. V.-
dc.date.accessioned2011-03-18T10:08:56Z
dc.date.available2011-03-18T10:08:56Z
dc.date.issued2010-02-05T00:00:00Z-
dc.description.abstractPortable biomimetic sensor devices for the express control of phenols content in water were developed. The synthetic binding sites mimicking active site of the enzyme tyrosinase were formed in the structure of free-standing molecularly imprinted polymer membranes. Molecularly imprinted polymer membranes with the catalytic activity were obtained by co-polymerization of the complex Cu (II)–catechol–urocanic acid ethyl ester with (tri)ethyleneglycoldimethacrylate, and oligourethaneacrylate. Addition of the elastic component oligourethaneacrylate provided formation of the highly cross-linked polymer with the catalytic activity in a form of thin, flexible, and mechanically stable membrane. High accessibility of the artificial catalytic sites for the interaction with the analyzed phenol molecules was achieved due to addition of linear polymer (polyethyleneglycol Mw 20,000) to the initial monomer mixture before the polymerization. As a result, typical semi-interpenetrating polymer networks (semi-IPNs) were formed. The cross-linked component of the semi-IPN was represented by the highly cross-linked catalytic molecularly imprinted polymer, while the linear one was represented by polyethyleneglycol Mw 20,000. Extraction of the linear polymer from the fully formed semi-IPN resulted in formation of large pores in the membranes’ structure. Concentration of phenols in the analyzed samples was detected using universal portable device oxymeter with the oxygen electrode in a close contact with the catalytic molecularly imprinted polymer membrane as a transducer. The detection limit of phenols detection using the developed sensor system based on polymers–biomimics with the optimized composition comprised 0.063 mM, while the linear range of the sensor comprised 0.063–1 mM. The working characteristics of the portable sensor devices were investigated. Storage stability of sensor systems at room temperature comprised 12 months (87%). As compared to traditional methods of phenols detection the developed sensor system is characterized by simplicity of operation, compactness, anden_UK
dc.identifier.citationT.A. Sergeyeva, O.A. Slinchenko, L.A. Gorbach, V.F. Matyushov, O.O. Brovko, S.A. Piletsky, L.M. Sergeeva, G.V. Elska, Catalytic molecularly imprinted polymer membranes: Development of the biomimetic sensor for phenols detection, Analytica Chimica Acta, Volume 659, Issues 1-2, 5 February 2010, Pages 274-279en_UK
dc.identifier.issn0003-2670-
dc.identifier.urihttp://dx.doi.org/10.1016/j.aca.2009.11.065-
dc.identifier.urihttp://dspace.lib.cranfield.ac.uk/handle/1826/4105
dc.language.isoen_UKen_UK
dc.publisherElsevier Science B.V., Amsterdam.en_UK
dc.subjectPhenolsen_UK
dc.subjectPolymers-biomimicsen_UK
dc.subjectPolymer catalystsen_UK
dc.subjectMolecularly imprinted polymersen_UK
dc.subjectSensoren_UK
dc.subjectTyrosinaseen_UK
dc.subjectEnvironmental monitoringen_UK
dc.titleCatalytic molecularly imprinted polymer membranes: Development of the biomimetic sensor for phenols detectionen_UK
dc.typeArticleen_UK

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