Paper-based devices for rapid diagnostics and testing sewage for early warning of COVID-19 outbreak

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dc.contributor.authorHui, Qingxin
dc.contributor.authorPan, Yuwei
dc.contributor.authorYang, Zhugen
dc.date.accessioned2020-12-18T15:30:31Z
dc.date.available2020-12-18T15:30:31Z
dc.date.issued2020-11-29
dc.description.abstractoronavirus disease (COVID-19), caused by SARS-CoV-2, evolved into a global pandemic in 2020, and the outbreak has taken an enormous toll on individuals, families, communities and societies around the world. One practical and effective strategy is to implement rapid case identification based on a rapid testing to respond to this public health crisis. Currently, the available technologies used for rapid diagnostics include RT-PCR, RT-LAMP, ELISA and NGS. Still, due to their different limitations, they are not well suited for rapid diagnosis in a variety of locations. Paper-based devices are alternative approaches to achieve rapid diagnosis, which are cost-effective, highly selective, sensitive, portable, and easy-to-use. In addition to individual virus screening, wastewater-based epidemiology has been emerged to be an effective way for early warning of outbreak within the population, which tests viral genome sequence to reflect information on the spread and distribution of the virus because SARS-CoV-2 can be shed into wastewater through the feces and urine from infected population. In this paper, we describe paper-based device as a low-cost and rapid sensor for both diagnosis and testing of sewage for early warning of outbreak. More importantly, the device has great potential for real-time detection in the field, without any advanced facilities or well-trained and skilled personnel, and provides early warning or timely intervention of an outbreak of pandemic.en_UK
dc.identifier.citationHui Q, Pan Y, Yang Z. (2020) Paper-based devices for rapid diagnostics and testing sewage for early warning of COVID-19 outbreak. Case Studies in Chemical and Environmental Engineering, Volume 2, September 2020 Article number 100064en_UK
dc.identifier.issn2666-0164
dc.identifier.urihttps://doi.org/10.1016/j.cscee.2020.100064
dc.identifier.urihttp://dspace.lib.cranfield.ac.uk/handle/1826/16100
dc.language.isoenen_UK
dc.publisherElsevieren_UK
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectPaper-based devicesen_UK
dc.subjectRapid diagnosisen_UK
dc.subjectWastewater-based epidemiologyen_UK
dc.subjectCOVID-19en_UK
dc.subjectEarly warning systemen_UK
dc.titlePaper-based devices for rapid diagnostics and testing sewage for early warning of COVID-19 outbreaken_UK
dc.typeArticleen_UK

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