Recent advances in microbial biosynthesis of C3 – C5 diols: Genetics and process engineering approaches

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dc.contributor.authorVivek, Narisetty
dc.contributor.authorHazeen, Sulfath Hakkim
dc.contributor.authorAlphy, Maria Paul
dc.contributor.authorKumar, Vinod
dc.contributor.authorMagdouli, Sara
dc.contributor.authorSindhu, Raveendran
dc.contributor.authorPandey, Ashok
dc.contributor.authorBinod, Parameswaran
dc.date.accessioned2021-01-12T13:53:33Z
dc.date.available2021-01-12T13:53:33Z
dc.date.issued2020-12-13
dc.description.abstractDiols derived from renewable feedstocks have significant commercial interest in polymer, pharmaceutical, cosmetics, flavors and fragrances, food and feed industries. In C3-C5 diols biological processes of 1,3-propanediol, 1,2-propanediol and 2,3-butanediol have been commercialized as other isomers are non-natural metabolites and lack natural biosynthetic pathways. However, the developments in the field of systems and synthetic biology paved a new path to learn, build, construct, and test for efficient chassis strains. The current review addresses the recent advancements in metabolic engineering, construction of novel pathways, process developments aimed at enhancing in production of C3-C5 diols. The requisites on developing an efficient and sustainable commercial bioprocess for C3-C5 diols were also discusseden_UK
dc.identifier.citationVivek N, Hazeena SH, Alphy MP, et al., (2020) Recent advances in microbial biosynthesis of C3 – C5 diols: Genetics and process engineering approaches. Bioresource Technology, Volume 322, February 2020, Article number 124527en_UK
dc.identifier.issn0960-8524
dc.identifier.urihttps://doi.org/10.1016/j.biortech.2020.124527
dc.identifier.urihttp://dspace.lib.cranfield.ac.uk/handle/1826/16159
dc.language.isoenen_UK
dc.publisherElsevieren_UK
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectRenewable diolsen_UK
dc.subjectPentanediolsen_UK
dc.subjectButanediolsen_UK
dc.subjectPropanediolsen_UK
dc.subjectMetabolic engineeringen_UK
dc.titleRecent advances in microbial biosynthesis of C3 – C5 diols: Genetics and process engineering approachesen_UK
dc.typeArticleen_UK

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