Advances in design of high-performance heterostructured scintillators for time-of-flight positron emission tomography

dc.contributor.authorKrause, Philip George
dc.contributor.authorRogers, Edith
dc.contributor.authorBizarri, Gregory
dc.date.accessioned2023-10-24T08:43:03Z
dc.date.available2023-10-24T08:43:03Z
dc.date.issued2023-10-10
dc.description.abstractCore to advancing time-of-flight positron emission tomography (ToF-PET) toward a less invasive, more flexible procedure with a higher diagnostic power is the development of enhanced radiation detector materials. One promising avenue is the development of heterostructured scintillators where multiple materials work in synergy to exceed the performance of each individual component. Applied to ToF-PET detectors, one component contributes predominantly to the absorption of gamma rays and the other to the creation of ultra-fast photons. Whilst other authors have proposed various concepts, heterostructured scintillators are still in their infancy and scientifically guiding their development remains a challenge. Toward this aim and based on simulation and modeling developments, heterostructure properties are directly linked to ToF-PET performance. This is made possible by redefining the notions of detector photo-peak efficiency and timing response, as defined for monolithic detectors, in the context of heterostructured scintillators. Their overall potential is then discussed as a function of the materials and design used. This provides a quantitative framework to rapidly and efficiently support the advancement of heterostructured detectors for ToF-PET technology.en_UK
dc.description.sponsorshipEngineering and Physical Sciences Research Council (EPSRC): EP/S013652/1en_UK
dc.identifier.citationKrause P, Rogers E, Bizarri G. (2024) Advances in design of high-performance heterostructured scintillators for time-of-flight positron emission tomography, Advanced Theory and Simulations, Volume 7, Issue 1, January 2024, Article Number 2300425en_UK
dc.identifier.issn2513-0390
dc.identifier.urihttps://doi.org/10.1002/adts.202300425
dc.identifier.urihttps://dspace.lib.cranfield.ac.uk/handle/1826/20429
dc.language.isoenen_UK
dc.publisherWileyen_UK
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectheterostructured radiation scintillatoren_UK
dc.subjectpositron emission tomographyen_UK
dc.subjectultra-fast timingen_UK
dc.titleAdvances in design of high-performance heterostructured scintillators for time-of-flight positron emission tomographyen_UK
dc.typeArticleen_UK

Files

Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
High‐performance_heterostructured_scintillators-2023.pdf
Size:
1.87 MB
Format:
Adobe Portable Document Format
Description:
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.63 KB
Format:
Item-specific license agreed upon to submission
Description: