Prospects on bio-based 2,3-butanediol and acetoin production: recent progress and advances

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dc.contributor.authorMaina, Sofia
dc.contributor.authorPrabhu, Ashish A.
dc.contributor.authorVivek, Narisetty
dc.contributor.authorVlysidis, Anestis
dc.contributor.authorKoutinas, Apostolis
dc.contributor.authorKumar, Vinod
dc.date.accessioned2021-06-30T10:34:50Z
dc.date.available2021-06-30T10:34:50Z
dc.date.issued2021-06-29
dc.description.abstractThe bio-based platform chemicals 2,3-butanediol (BDO) and acetoin have various applications in chemical, cosmetics, food, agriculture, and pharmaceutical industries, whereas the derivatives of BDO could be used as fuel additives, polymer and synthetic rubber production. This review summarizes the novel technological developments in adapting genetic and metabolic engineering strategies for selection and construction of chassis strains for BDO and acetoin production. The valorization of renewable feedstocks and bioprocess development for the upstream and downstream stages of bio-based BDO and acetoin production are discussed. The techno-economic aspects evaluating the viability and industrial potential of bio-based BDO production are presented. The commercialization of bio-based BDO and acetoin production requires the utilization of crude renewable resources, the chassis strains with high fermentation production efficiencies and development of sustainable purification or conversion technologies.en_UK
dc.identifier.citationMaina S, Prabhu AA, Vivek N, et al., (2022) Prospects on bio-based 2,3-butanediol and acetoin production: recent progress and advances. Biotechnology Advances, Volume 54, January-February 2022, Article number 107783en_UK
dc.identifier.issn0734-9750
dc.identifier.urihttps://doi.org/10.1016/j.biotechadv.2021.107783
dc.identifier.urihttp://dspace.lib.cranfield.ac.uk/handle/1826/16830
dc.language.isoenen_UK
dc.publisherElsevieren_UK
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject2,3-Butanediolen_UK
dc.subjectAcetoinen_UK
dc.subjectMetabolic engineeringen_UK
dc.subjectBioprocess developmenten_UK
dc.subjectDownstream processingen_UK
dc.subjectTechno-economic evaluationen_UK
dc.subjectPlatform chemicalsen_UK
dc.titleProspects on bio-based 2,3-butanediol and acetoin production: recent progress and advancesen_UK
dc.typeArticleen_UK

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