The design and manufacture of biomedical surfaces

Date published

2007-08-01T00:00:00Z

Free to read from

Supervisor/s

Journal Title

Journal ISSN

Volume Title

Publisher

Technische Rundschau, Hallwag Publishers; 1999

Department

Type

Article

ISSN

0007-8506

Format

Citation

J.J. Ramsden, D.M. Allen, D.J. Stephenson, J.R. Alcock, G.N. Peggs, G. Fuller and G. Goch. The design and manufacture of biomedical surfaces. Cirp Annals-Manufacturing Technology, 2007, Volume 56, Issue 2, pp687-711

Abstract

Surfaces are the primary place of contact between a biomaterial and its host organism. Typically, prostheses have to fulfil demanding structural and mechanical requirements, yet the material best for those functions may be bio- incompatible. Surface treatment or coating provides a means to overcome that problem, which means both integration within the host physiology and stabilization with respect to corrosion and wear. The adsorption of biomacromolecules is pivotal for biocompatibility. The impossibility of keeping proteins away from most implants means that very careful consideration has to be given to this aspect, and both prevention (for bloodstream implants) and promotion (for bone replacement and repair) occur with equal importance. This paper also considers the metrology of relevant physical and chemical aspects of surfaces.

Description

Software Description

Software Language

Github

Keywords

DOI

Rights

Relationships

Relationships

Supplements

Funder/s