Citation:
Michael J. Whitcombe, Iva Chianella, Lee Larcombe, Sergey A. Piletsky, James Noble, Robert Porter, Adrian Horgan. The rational development of molecularly imprinted polymer-based sensors for
protein detection. Chemical Society reviews, 2011, vol 40, pp1547-1571
Abstract:
The detection of specific proteins as biomarkers of disease, health status,
environmental monitoring, food quality, control of fermenters and civil defence
purposes means that biosensors for these targets will become increasingly more
important. Among the technologies used for building specific recognition
properties, molecularly imprinted polymers (MIPs) are attracting much attention.
In this critical review we describe many methods used for imprinting recognition
for protein targets in polymers and their incorporation with a number of
transducer platforms with the aim of identifying the most promising approaches
for the preparation of MIP-based protein sensors (277 references).
