Citation:
Mijangos I, Navarro-Villoslada F, Guerreiro A, et al., (2006) Influence of initiator and different polymerisation conditions on performance of molecularly imprinted polymers, Biosensors and Bioelectronics, Volume 22, Issue 3, Selected Papers from Synthetic Receptors 2005, 15 September 2006, Pages 381-387
Abstract:
A set of polymers was imprinted with (−)-ephedrine using two different initiators. A chemometrics approach was used to optimise experiments aimed at analysis of the interplay of parameters such as polymerisation time, temperature and percentage of initiator. The results presented demonstrate the importance of keeping the right balance between these various parameters of polymerisation conditions. It is shown that enhancing one single parameter such as polymer rigidity does not necessarily improve polymer performance. In general it could be concluded that MIPs should be synthesised over a long period of time using low concentration of initiator and low temperature. The best selectivity was achieved for polymers prepared by photo-initiation with 2,2-dimethoxy-2-phenylacetophenone as initiatotor
