Citation:
Alessandra Bossi, Claudio Rivetti, Laura Mangiarotti, Michael J. Whitcombe, Anthony P.F. Turner, Sergey A. Piletsky, Patterned gallium surfaces as molecular mirrors, Biosensors and Bioelectronics, Volume 23, Issue 2, 30 September 2007, Pages 290-294
Abstract:
An entirely new means of printing molecular information on a planar film,
involving casting nanoscale impressions of the template protein molecules in
molten gallium, is presented here for the first time. The metallic imprints not
only replicate the shape and size of the proteins used as template. They also
show specific binding for the template species. Such a simple approach to the
creation of antibody-like properties in metallic mirrors can lead to
applications in separations, microfluidic devices, and the development of new
optical and electronic sensors, and will be of interest to chemists, materials
scientists, analytical specialists, and electronic engineers.