Age-related trends in the trabecular micro-architecture of the medial clavicle: is it of use in forensic science?

Show simple item record

dc.contributor.author McGivern, Hannah
dc.contributor.author Greenwood, Charlene
dc.contributor.author Márquez-Grant, Nicholas
dc.contributor.author Kranioti, Elena F.
dc.contributor.author Xhemali, Bledar
dc.contributor.author Zioupos, Peter
dc.date.accessioned 2020-01-27T16:50:46Z
dc.date.available 2020-01-27T16:50:46Z
dc.date.issued 2020-01-22
dc.identifier.citation McGivern H, Greenwood C, Marquez-Grant N, Kranioto EF, Xhemali B & Zioupos P. Age-related trends in the trabecular micro-architecture of the medial clavicle: is it of use in forensic science? Frontiers in Bioengineering and Biotechnology, Volume 7, 2020, Article number 467 en_UK
dc.identifier.issn 2296-4185
dc.identifier.uri https://doi.org/10.3389/fbioe.2019.00467
dc.identifier.uri http://dspace.lib.cranfield.ac.uk/handle/1826/15023
dc.description.abstract The mechanical and structural properties of bone are known to change significantly with age. Within forensic and archaeological investigations, the medial end of the clavicle is typically used for estimating the age-at-death of an unknown individual. Although, this region of the skeleton is of interest to forensic and clinical domains, alterations beyond the macro-scale have not been fully explored. For this study, non-destructive micro-computed tomography (µ-CT) was employed to characterize structural alterations to the cancellous bone of the medial clavicle. Fresh human cadaveric specimens (12-59 years) obtained at autopsy were utilized for this study, and were scanned with a voxel size of ∼83µm. Morphometric properties were quantified and indicated that the bone volume, connectivity density, mineral density, and number of trabeculae decreased with age, while the spacing between the trabeculae increased with age. In contrast to other sub-regions of the skeleton, trabecular thickness, and degree of anisotropy did not correlate with age. Collectively, this could suggest that the network is becoming increasingly perforated with age rather than exhibiting trabecular thinning. These results are used in the context of deriving a potential protocol for forensic investigations by using this particular and largely unexplored region of the skeleton, and provide inspiration for future experiments concerning micro-architectural and small scale changes in other regions of the human skeleton. en_UK
dc.language.iso en en_UK
dc.publisher Frontiers en_UK
dc.rights Attribution 4.0 International *
dc.rights.uri http://creativecommons.org/licenses/by/4.0/ *
dc.subject clavicle en_UK
dc.subject cancellous bone en_UK
dc.subject micro-computed tomography en_UK
dc.subject forensic science en_UK
dc.subject biomechanics en_UK
dc.subject Aging en_UK
dc.title Age-related trends in the trabecular micro-architecture of the medial clavicle: is it of use in forensic science? en_UK
dc.type Article en_UK


Files in this item

The following license files are associated with this item:

This item appears in the following Collection(s)

Show simple item record

Attribution 4.0 International Except where otherwise noted, this item's license is described as Attribution 4.0 International

Search CERES


Browse

My Account

Statistics