Potential and limitations of Klebsiella pneumoniae as a microbial cell factory utilizing glycerol as the carbon source

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dc.contributor.author Kumar, Vinod
dc.contributor.author Park, Sunghoon
dc.date.accessioned 2017-12-18T11:31:47Z
dc.date.available 2017-12-18T11:31:47Z
dc.date.issued 2017-10-19
dc.identifier.citation Vinod Kumar, Sunghoon Park, Potential and limitations of Klebsiella pneumoniae as a microbial cell factory utilizing glycerol as the carbon source, Biotechnology Advances, Volume 36, Issue 1, January–February 2018, Pages 150-167 en_UK
dc.identifier.issn 0734-9750
dc.identifier.uri https://doi.org/10.1016/j.biotechadv.2017.10.004
dc.identifier.uri http://dspace.lib.cranfield.ac.uk/handle/1826/12771
dc.description.abstract Klebsiella pneumoniae is a Gram-negative facultative anaerobe that metabolizes glycerol efficiently under both aerobic and anaerobic conditions. This microbe is considered an outstanding biocatalyst for transforming glycerol into a variety of value-added products. Crude glycerol is a cheap carbon source and can be converted by K. pneumoniae into useful compounds such as lactic acid, 3-hydroxypropionic acid, ethanol, 1,3-propanediol, 2,3-butanediol, and succinic acid. This review summarizes glycerol metabolism in K. pneumoniae and its potential as a microbial cell factory for the production of commercially important acids and alcohols. Although many challenges remain, K. pneumoniae is a promising workhorse when glycerol is used as the carbon source. en_UK
dc.language.iso en en_UK
dc.publisher Elsevier en_UK
dc.rights Attribution-NonCommercial-NoDerivatives 4.0 International *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/ *
dc.subject Klebsiella pneumoniae en_UK
dc.subject Glycerol en_UK
dc.subject 3-Hydroxypropionic acid en_UK
dc.subject 1,3-Propanediol en_UK
dc.subject 2,3-Butanediol en_UK
dc.subject Lactic acid en_UK
dc.subject Ethanol en_UK
dc.title Potential and limitations of Klebsiella pneumoniae as a microbial cell factory utilizing glycerol as the carbon source en_UK
dc.type Article en_UK


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