Computional selection of synthetic antigens for application in diagnostic, vaccine and therapeutic development
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2006-02
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Cranfield University
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Thesis or dissertation
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Abstract
This work set out to apply computational tools and biophysics principles to develop a systematic approach to the rational selection of synthetic antigens from appropriate DNA sequences. The wider potential to the rapid development of diagnostics will be demonstrated by application towards a chlamydia-specific immunodiagnostic, and the potential for vaccine and therapeutic development will be discussed.
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© Cranfield University, 2006. All rights reserved. No part of this publication may be reproduced without the written permission of the copyright holder.