Browsing by Subject "DNA methylation"

Browsing by Subject "DNA methylation"

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  • Changes in DNA methylation from pre- to post-adolescence are associated with pubertal exposures 
    Han, Luhang; Zhang, Hongmei; Kaushal, Akhilesh; Rezwan, Faisal I.; Kadalayil, Latha; Karmaus, Wilfried; Henderson, A. John; Relton, Caroline L.; Ring, Susan; Arshad, Syed Hasan; Holloway, John W. (BMC (part of Springer Nature), 2019-12-02)
    Background Adolescence is a period characterized by major biological development, which may be associated with changes in DNA methylation (DNA-M). However, it is unknown to what extent DNA-M varies from pre- to post-adolescence, ...
  • Changes of DNA methylation are associated with changes in lung function during adolescence 
    Sunny, Shadia Khan; Zhang, Hongmei; Rezwan, Faisal I.; Relton, Caroline L.; Henderson, A. John; Merid, Simon Kebede; Melén, Erik; Hallberg, Jenny; Arshad, Syed Hasan; Ewart, Susan; Holloway, John W. (BioMed Central, 2020-04-07)
    Background Adolescence is a significant period for the gender-dependent development of lung function. Prior studies have shown that DNA methylation (DNA-M) is associated with lung function and DNA-M at some cytosine-pho ...
  • DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies 
    Vehmeijer, Florianne O. L.; Küpers, Leanne K.; Sharp, Gemma C.; Salas, Lucas A.; Lent, Samantha; Jima, Dereje D.; Tindula, Gwen; Reese, Sarah; Qi, Cancan; Gruzieva, Olena; Page, Christian; Rezwan, Faisal I. (BioMed Central, 2020-11-25)
    Background DNA methylation has been shown to be associated with adiposity in adulthood. However, whether similar DNA methylation patterns are associated with childhood and adolescent body mass index (BMI) is largely ...
  • Epigenome-wide association study reveals duration of breastfeeding is associated with epigenetic differences in children 
    Sherwood, William B.; Kothalawala, Dilini M.; Kadalayil, Latha; Ewart, Susan; Zhang, Hongmei; Karmaus, Wilfried; Arshad, Syed Hasan; Holloway, John W.; Rezwan, Faisal I. (MDPI, 2020-05-20)
    Several small studies have shown associations between breastfeeding and genome-wide DNA methylation (DNAm). We performed a comprehensive Epigenome-Wide Association Study (EWAS) to identify associations between breastfeeding ...
  • The functional role of methylated short tandem repeats in early mouse development 
    Deakin, Greg (Cranfield UniversityCranfield Health, 2011-08)
    Short tandem repeats, or microsatellites are ubiquitous throughout all genomes that have been explored. In common with other sequences, the DNA in microsatellites has DNA marks in the form of chromatin methylation. Regulation ...
  • Gaussian Bayesian network comparisons with graph ordering unknown 
    Zhang, Hongmei; Huang, Xianzheng; Han, Shengtong; Rezwan, Faisal I.; Karmaus, Wilfried; Arshad, Syed Hasan; Holloway, John W. (Elsevier, 2020-12-26)
    A Bayesian approach is proposed that unifies Gaussian Bayesian network constructions and comparisons between two networks (identical or differential) for data with graph ordering unknown. When sampling graph ordering, to ...
  • Pre-adolescence DNA methylation is associated with BMI status change from pre-to post-adolescence 
    Wang, Jiajing; Zhang, Hongmei; Rezwan, Faisal I.; Relton, Caroline L.; Hasan Arshad, S.; Holloway, John W. (BMC (part of Springer Nature), 2021-03-25)
    Background: Previous studies have shown that DNA methylation (DNAm) is associated with body mass index (BMI). However, it is unknown whether DNAm at pre-adolescence is associated with BMI status transition from pre- to ...
  • Role of DNA methylation in the association of lung function with body mass index: a two-step epigenetic Mendelian randomisation study 
    Amaral, André F. S.; Imboden, Medea; Wielscher, Matthias; Rezwan, Faisal I.; Minelli, Cosetta; Garcia-Aymerich, Judith; Peralta, Gabriela P.; Auvinen, Juha; Jeong, Ayoung; Schaffner, Emmanuel; Beckmeyer-Borowko, Anna; Holloway, John W.; Jarvelin, Marjo-Riitta; Probst-Hensch, Nicole; Jarvis, Deborah L. (BioMed Central, 2020-06-16)
    Background Low lung function has been associated with increased body mass index (BMI). The aim of this study was to investigate whether the effect of BMI on lung function is mediated by DNA methylation. Methods We ...