Browsing by Author "Zhu, H."
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Item Open Access Integration of polymer nanocomposites technologies for automotive applications: opportunities and environmental health challenges(2008-05-14T00:00:00Z) Njuguna, James A. K.; Peña, I.; Zhu, H.; Rocks, Sophie A.; Blazquez, Maria; Desai, S. A.; Pielichowski, KrzysztofThe concept of nanostructured materials design is gaining widespread importance among the automotive industry. Although employment of nanotechnology in current and future automotives will go long way in solving energy crises, it is necessary to understand both the hazards associated with nanomaterials and the levels of exposure that are likely to occur. The existing knowledge in these areas is quite limited and it will be necessary in the near future. This paper highlights these key issues and goes a long way in pointing recent activities on environmental risks of nanomaterials. Some research directions are given and existing automotive opportunities and applications explored.Item Open Access The mechanism of cryptolepine-induced cell death(Asian Network for Scientific Information, 2008-12-31T00:00:00Z) Ansah, C.; Zhu, H.; Goderham, N. J.The objective of the present study was to use morphological and biochemical approaches to characterize the mode of CLP-induced cell death. Using a differential staining technique, a Chinese Hamster fibroblast cell line (V79 cells) and a human lymphoblastoid cell line (MCL-5) showed morphology consistent with apoptosis after treatment with CLP. In contrast, HepG2, a human hepatoma cell line showed morphology that was more like necrosis after treatment with CLP. Using annexin V staining for apoptotic cells, MCL-5 cells showed a three fold increase in apoptosis within 6 h. Although we observed only a marginal increase in BAX protein expression, cytochrome c was released into the cytosol of CLP-treated MCL-5 cells. Furthermore, procaspase-3 was processed into the active caspase-3 (17 kDa). Consistent with the caspase-3 activation, PARP was cleaved to the typical 85 kDa fragment confirming apoptosis as the mode of cell death in CLP-treated MCL-5 cells. However, there was no evidence of increased BAX expression, cytochrome c release, caspase activation or PARP cleavage in CLP-treated HepG2 cells. This observation together with the morphology of CLP- treated HepG2 cells indicates that in contrast to MCL-5 cells, the CLP-mediated demise of HepG2 cells is not apoptotic.Item Open Access Using Coriolis Mass Flowmeter for Wet Gas Metering(Institute of Measurement & Control, 2010-07-31T00:00:00Z) Geng, Y. F.; Yeung, Hoi; Cao, Yi; Xing, L. C.; Zhu, H.; Drahm, W.Established wet gas metering techniques are typically based on differential pressure devices, and their measurement accuracy is still unsatisfactory to natural gas industry. Coriolis mass flowmeter (CMF) is the most superior flow measurement technology at now, it can provide mass flowrate and density output simultaneously. Putting CMF into wet gas metering may be a reasonable and high accuracy solution to natural gas industry demands. The problems and advantages of CMF in gas-liquid two-phase flow metering has been analyzed, a serious experiments has been carried out to test the possibility and feasibility of CMF as wet gas meter. Experimental conclusions are promising,CMF can work properly in wet gas metering condition, and the repeatability test of CMF is perfect, and the relationship between the true mass flowrate and CMF readings are almost linear. When gas flowrate is kept to a constant, CMF can follow the variations of liquid flowrate accurately. At last, some open problems deserving further investigation are propose