Browsing by Author "Yan, Hao"
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Item Open Access Ant-behavior inspired intelligent nanonet for targeted drug delivery in cancer therapy(IEEE, 2020-04-01) Lin, Lin; Huang, Fupeng; Yan, Hao; Liu, Fuqiang; Guo, WeisiTargeted drug delivery system is believed as one of the most promising solutions for cancer treatment due to its low-dose requirement and less side effects. However, both passive targeting and active targeting rely on systemic blood circulation and diffusion, which is actually not the real “active” drug delivery. In this paper, an ant-behavior inspired nanonetwork composing of intelligent nanomachines is proposed. A big intelligent nanomachine take small intelligent nanomachines and drugs to the vicinity of of the tumor area. The small intelligent nanomachines can coordinate with each other to find the most effective path to the tumor cell for drug transportation. The framework and mechanism of this cooperative network are proposed. The route finding algorithm is presented. The convergence performance is analytically analyzed where the influence of the factors such as molecule degradation rate, home-destination distance, number of small nanomachines to the convergence is presented. Finally the simulation results validate the effectiveness of the proposed mechanism and analytical analysisItem Open Access Molecular communication via subdiffusion with a spherical absorbing receiver(IEEE, 2020-06-09) Huang, Shuai; Lin, Lin; Xu, Juan; Guo, Weisi; Yan, HaoIn molecular communication (MC), the motion of information molecules in the medium is usually described by the Brownian motion and governed by the Fick’s laws. However, there are some potential scenarios of MC where the kinetics of information molecules is non-Fickian. In this letter, we investigate one of this kind of MC. The manner of information molecules in the channel is subdiffusion. A three-dimensional MC system with a spherical absorbing receiver is considered. The subdiffusion channel is analyzed. The closed-form expressions of the first hitting probability and its peak time are given. Furthermore, we investigate the performance of MC by timing and amplitude modulation schemes in a subdiffusion channel. The error probability for both modulation schemes is analyzedItem Open Access Signal detection for molecular MIMO communications with asymmetrical topology(IEEE, 2020-06-22) Wu, Cong; Lin, Lin; Guo, Weisi; Yan, HaoMolecular communication (MC) has attracted people’s attention due to its potential applications at the micro- to nano-scale. In MC, the transmission rate is usually very low due to the slow diffusion of information molecules and therefore multiple-input multiple-output (MIMO) system is introduced. However, severe interference occurs when the same types of information molecules are used at different transmission antennas. Up to now, most literature focuses on MIMO systems with symmetrical topology. In this paper, a molecular MIMO communication system with asymmetrical topology, where the number of transmission antennas is not equal to that of the reception antennas, is investigated. The zero-forcing (ZF) detection approach is proposed and discussed for three cases, i.e., the number of transmission antennas is smaller than, equal to and larger than the number of the reception antennas. Considering the inter-link interference (ILI) and the inter-symbol interference (ISI), the error probability of ZF detection is derived and comparisons are made with existing molecular MIMO detection method. Besides, the adaptive observation time for each reception antenna is derived for better performance. Numerical results show that ZF detection performs better than the existing molecular MIMO detection method when the ILI is large