Browsing by Author "Lin, Lin"
Now showing 1 - 6 of 6
Results Per Page
Sort Options
Item Open Access Ant-behavior inspired intelligent nanonet for targeted drug delivery in cancer therapy(IEEE, 2020-04-01) Lin, Lin; Huang, Fupeng; Yan, Hao; Liu, Fuqiang; Guo, WeisiTargeted drug delivery system is believed as one of the most promising solutions for cancer treatment due to its low-dose requirement and less side effects. However, both passive targeting and active targeting rely on systemic blood circulation and diffusion, which is actually not the real “active” drug delivery. In this paper, an ant-behavior inspired nanonetwork composing of intelligent nanomachines is proposed. A big intelligent nanomachine take small intelligent nanomachines and drugs to the vicinity of of the tumor area. The small intelligent nanomachines can coordinate with each other to find the most effective path to the tumor cell for drug transportation. The framework and mechanism of this cooperative network are proposed. The route finding algorithm is presented. The convergence performance is analytically analyzed where the influence of the factors such as molecule degradation rate, home-destination distance, number of small nanomachines to the convergence is presented. Finally the simulation results validate the effectiveness of the proposed mechanism and analytical analysisItem Open Access Error performance and mutual information for IoNT interface system(IEEE, 2022-02-23) Li, Yu; Lin, Lin; Guo, Weisi; Zhang, Dingguo; Yang, KunMolecular communication and the internet of nanothings (IoNTs) are emerging research hotspots recently, which show great potential in biomedical applications inside the human body. However, how to transmit information from inside body IoNTs to outside devices is seldomly studied. It is well known that the nervous system is responsible for perceiving the external environment and controlling the feedback signals. It exactly works like an interface between the external and internal environment. Inspired by this, this paper proposes a novel concept that one can use the modified nervous system to communicate between IoNT devices and in vitro equipments. In our proposed system, nanomachines transmit signals via stimulating the nerve fiber by the electrode. Then the signals transmit along nerve fibers and muscle fibers. Finally, they cause changes in surface electromyography (sEMG) signals which can be decoded by the body surface receiver. The paper presents the framework of this entire through-body communication system. Each part of the framework is also mathematically modeled. The error probability and mutual information of the system are derived from the communication theory perspective, which are evaluated and analyzed through numerical results. This study can pave the way for the connection of IoNT in vivo to external networks.Item Open Access Molecular communication via subdiffusion with a spherical absorbing receiver(IEEE, 2020-06-09) Huang, Shuai; Lin, Lin; Xu, Juan; Guo, Weisi; Yan, HaoIn molecular communication (MC), the motion of information molecules in the medium is usually described by the Brownian motion and governed by the Fick’s laws. However, there are some potential scenarios of MC where the kinetics of information molecules is non-Fickian. In this letter, we investigate one of this kind of MC. The manner of information molecules in the channel is subdiffusion. A three-dimensional MC system with a spherical absorbing receiver is considered. The subdiffusion channel is analyzed. The closed-form expressions of the first hitting probability and its peak time are given. Furthermore, we investigate the performance of MC by timing and amplitude modulation schemes in a subdiffusion channel. The error probability for both modulation schemes is analyzedItem Open Access Molecular physical layer for 6G in wave-denied environments(IEEE, 2021-06-03) Guo, Weisi; Abbaszadeh, Mahmoud; Lin, Lin; Charmet, JeromeThe sixth generation (6G) of wireless systems are likely to operate in environments and scales that wireless services have not penetrated effectively. Many of these environments are not suitable for efficient data bearing wave propagation. Molecular signals have the potential to deliver information by exploiting both new modulation mechanisms via chemical encoding and new multi-scale propagation physics. While the fusion of biophysical models and communication theory has rapidly advanced the molecular communication field, there is a lack of real-world macro-scale applications. Here, we introduce application areas in defense and security, ranging from underwater search and rescue to covert communications; and cyber-physical systems, such as using molecular signals for health monitoring in underground networked systems. These engineering applications not only demand new wireless communication technologies ranging from DNA encoding to molecular graph signal processing, but also demonstrate the potential for molecular communication to contribute in traditional but challenging engineering areas. Together, it is increasingly believed that molecular communication can be a new physical layer for 6G, accessing and extracting data from extreme wave-denied environments.Item Open Access Physical-layer counterattack strategies for the internet of bio-nano things with molecular communication(IEEE, 2023-06-06) Huang, Yu; Wen, Miaowen; Lin, Lin; Li, Bin; Wei, Zhuangkun; Tang, Dong; Li, Jun; Duan, Wei; Guo, WeisiMolecular communication (MC) is an emerging new communication paradigm where information is conveyed by chemical signals. It has been recognized as one of the most promising physical layer techniques for the future Internet of Bio-Nano Things (IoBNT), which enables revolutionary applications beyond our imagination. Compared with conventional communication systems, MC typically demands a higher security level as the IoBNT is deeply associated with the biochemical process. Against this background, this article first discusses the security and privacy issues of IoBNT with MC. Then, the physical-layer countermeasures against the threat are presented from an interdisciplinary perspective concerning data science, signal processing techniques, and the biochemical properties of MC. Correspondingly, both the keyless and key-based schemes are conceived and revisited. Finally, some open research issues and future research directions for secrecy enhancement in IoBNT with MC are put forward.Item Open Access Signal detection for molecular MIMO communications with asymmetrical topology(IEEE, 2020-06-22) Wu, Cong; Lin, Lin; Guo, Weisi; Yan, HaoMolecular communication (MC) has attracted people’s attention due to its potential applications at the micro- to nano-scale. In MC, the transmission rate is usually very low due to the slow diffusion of information molecules and therefore multiple-input multiple-output (MIMO) system is introduced. However, severe interference occurs when the same types of information molecules are used at different transmission antennas. Up to now, most literature focuses on MIMO systems with symmetrical topology. In this paper, a molecular MIMO communication system with asymmetrical topology, where the number of transmission antennas is not equal to that of the reception antennas, is investigated. The zero-forcing (ZF) detection approach is proposed and discussed for three cases, i.e., the number of transmission antennas is smaller than, equal to and larger than the number of the reception antennas. Considering the inter-link interference (ILI) and the inter-symbol interference (ISI), the error probability of ZF detection is derived and comparisons are made with existing molecular MIMO detection method. Besides, the adaptive observation time for each reception antenna is derived for better performance. Numerical results show that ZF detection performs better than the existing molecular MIMO detection method when the ILI is large