Browsing by Author "Larcombe, L."
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Item Open Access Computional selection of synthetic antigens for application in diagnostic, vaccine and therapeutic development(Cranfield University, 2006-02) Larcombe, L.; Woodman, Anthony C.This work set out to apply computational tools and biophysics principles to develop a systematic approach to the rational selection of synthetic antigens from appropriate DNA sequences. The wider potential to the rapid development of diagnostics will be demonstrated by application towards a chlamydia-specific immunodiagnostic, and the potential for vaccine and therapeutic development will be discussed.