Citation:
Andrew C. Barton, Stuart D. Collyer, Frank Davis, Davinia D. Gornall, Karen A. Law, Emma C. D. Lawrence, Daniel W. Mills, Suzy Myler, Jeanette A. Pritchard, Mark Thompson and Seamus P. J. Higson, Sonochemically fabricated microelectrode arrays for biosensors offering widespread applicability. Part I, Biosensors and Bioelectronics, Volume 20, Issue 2, 15 September 2004, Pages 328-337
Abstract:
A novel and patented procedure is described for the sonochemical fabrication of
a new class of microelectrode array based sensor with electrode element
populations of up to 2 x 105 cm-2. For some years it has been accepted that
microelectrode arrays offer an attractive route for lowering minimum limits of
detection and imparting stir (convectional mass transport) independence to
sensor responses; despite this no commercial biosensors, to date, have employed
microelectrode arrays, largely due to the cost of conventional fabrication
routes that have not proved commercially viable for disposable devices.
Biosensors formed by our sonochemical approach offer unrivalled sensitivity and
impart stir independence to sensor responses. This format lends itself for mass
fabrication due to the simplicity and inexpensiveness of the approach; in the
first instance impedimetric and amperometric sensors are reported for glucose as
model systems. Sensors already developed for ethanol, oxalate and a number of
pesticide determinations will be reported in subsequent publications.
