Browsing by Author "Stebbeds, William Joshua David"

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The effect of oxidation on the stability of G-quadruplex DNA : implications for oncogene expression

Stebbeds, William Joshua David (Cranfield University, 2011-10)

G-quadruplexes (G4-DNA) are a class of secondary structures formed from Guanine rich sequences. In recent years these structures have been implicated in both telomere maintenance and oncogene expression, and have been shown ...
An in silico study of the differential effect of oxidation on two biologically relevant G-quadruplexes: Possible implications in oncogene expression

Stebbeds, William Joshua David; Lunec, Joseph; Larcombe, L. D. (Public Library of Science (PLoS), 2012-08-22)

G-quadruplex structures, formed from guanine rich sequences, have previously been shown to be involved in various physiological processes including cancer-related gene expression. Furthermore, G-quadruplexes have been found ...

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