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Browsing by Author "Stone, Nicholas"

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Study of calcification formation and disease diagnostics utilising advanced vibrational spectroscopy

Kerssens, Marleen Maartje (Cranfield University, 2012-10)

The accurate and safe diagnosis of breast cancer is a significant societal issue, with annual disease incidence of 48,000 women and around 370 men in the UK. Early diagnosis of the disease allows more conservative treatments ...
A study of FT-IR spectroscopy for the identification and classifcation of haematological malignancies

Babrah, Jaspreet (Cranfield University, 2009-06)

The aim of the work presented in this thesis was to explore the use of FT-IR spectroscopy, as a complementary clinical tool for haematological laboratory analysis. FT-IR spectra were measured from air-dried and frozen ...
Study of Raman spectroscopy for the early detection and classification of malignancy in oesophageal tissue

Kendall, Catherine (Cranfield University, 2002-10)

Raman Spectroscopy for the identification and classification of malignancy in the oesophagus has been demonstrated in this thesis. The potential of Raman spectroscopy in this field is twofold; as a adjunct for the ...
A time-course Raman spectroscopic analysis of spontaneous in vitro microcalcifications in a breast cancer cell line

Bouzy, Pascaline; O’Grady, Shane; Madupalli, Honey; Tecklenburg, Mary; Rogers, Keith; Palombo, Francesca; Morgan, Maria P.; Stone, Nicholas (Nature Publishing Group, 2021-06-11)

Microcalcifications are early markers of breast cancer and can provide valuable prognostic information to support clinical decision-making. Current detection of calcifications in breast tissue is based on X-ray mammography, ...
Towards automated classification of clinical optimal coherence tomography (OCT) data obtained from dense tissues

Bazant-Hegemark, Florian (Cranfield University, 2008)

Cervical cancer can be prevented if its precursors are recognised. Those lesions that justify preventive treatment are currently identified using methods that suffer from delayed results, false positives and subjective ...
Translating microcalcification biomarker information into the laboratory: a preliminary assessment utilizing core biopsies obtained from sites of mammographic calcification

Lyburn, Iain D.; Scott, Robert; Cornford, Eleanor; Bouzy, Pascaline; Stone, Nicholas; Greenwood, Charlene; Bouybayoune, Ihsanne; Pinder, Sarah E.; Rogers, Keith (Elsevier, 2024-03-12)

The potential of breast microcalcification chemistry to provide clinically valuable intelligence is being increasingly studied. However, acquisition of crystallographic details has, to date, been limited to high brightness, ...
The use of Raman spectroscopy for the intra-operative assessment of axillary lymph nodes in breast cancer

Horsnell, Jonathan (Cranfield University, 2012-05)

Breast cancer remains a significant cause of morbidity and mortality. Assessment of the axillary lymph nodes is part of the staging of the disease. Advances in surgical management of breast cancer have seen a move towards ...
Vibrational spectroscopy for the rapid and early diagnosis of leukaemias and lymphomas

Jackson, Olivia (Cranfield University, 2013-11)

This thesis aimed to investigate vibrational spectroscopies for the identification of biochemical markers of leukaemias and lymphomas. In a preliminary study using the blood proteins albumin, fibrinogen and globulin, Drop ...

Browsing by Author "Stone, Nicholas"

Browsing by Author "Stone, Nicholas"

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