Browsing by Author "Piletsky, Sergey A."

Browsing by Author "Piletsky, Sergey A."

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  • Molecularly imprinted polymers for protome analysis 
    Bonini, Francesca (Cranfield University, 2008-01)
    Fast and efficient methods for the detection of insurgence and progression of diseases are at the basis of modern diagnostics and medicine. In this concern, biomarkers represent a powerful diagnostic tool, as their ...
  • New approach in multipurpose optical diagnostics: fluorescence based assay for simultaneous determination of physicochemical parameters 
    Moczko, Ewa (Cranfield University, 2009-09)
    The development of sensors assays for comprehensive characterisation of biological samples and effective minimal-invasive diagnostics is highly prioritised. Last decade this research area has been actively developing due ...
  • New reactive polymer for protein immobilisation on sensor surfaces 
    Kyprianou, Dimitris; Guerreiro, Antonio R.; Chianella, Iva; Piletska, Elena V.; Fowler, Steven A.; Karim, Kal; Whitcombe, Michael J.; Turner, Anthony P. F.; Piletsky, Sergey A. (Elsevier Science B.V., Amsterdam., 2009-01-01)
    Immobilisation of biorecognition elements on transducer surfaces is a key step in the development of biosensors. The immobilisation needs to be fast, cheap and most importantly should not affect the biorecognition activity ...
  • A new reactive polymer suitable for covalent immobilisation and monitoring of primary amines 
    Piletska, Elena V.; Piletsky, Sergey A.; Subrahmanyam, S.; Turner, Anthony P. F. (Elsevier Science B.V., Amsterdam., 2001-04-01)
    A new polymer able to react with primary amines was synthesised from allyl mercaptan, o-phtalic dialdehyde and ethylene glycol dimethacrylate by radical polymerisation. Reactive thioacetale formed by allyl mercaptan and ...
  • Novel linear polymers able to inhibit bacterial quorum sensing 
    Cavaleiro, Eliana; Duarte, Ana Sofia; Esteves, Ana Cristina; Correia, António; Whitcombe, Michael J.; Piletska, Elena V.; Piletsky, Sergey A.; Chianella, Iva (Wiley, 2015-01-28)
    Bacterial phenotypes, such as biofilm formation, antibiotic resistance and virulence expression, are associated with quorum sensing. Quorum sensing is a density-dependent regulatory system of gene expression controlled by ...
  • Optical assay for biotechnology and clinical diagnosis 
    Moczko, Ewa; Cauchi, Michael; Turner, Claire; Meglinski, I. V.; Piletsky, Sergey A. (IEEE Institute of Electrical and Electronics, 2011-12-31)
    In this paper, we present an optical diagnostic assay consisting of a mixture of environmental-sensitive fluorescent dyes combined with multivariate data analysis for quantitative and qualitative examination of biological ...
  • Oxytetracycline recovery from aqueous media using computationally designed molecularly imprinted polymers 
    Rodríguez Dorado, R.; Carro, A. M.; Chianella, Iva; Karim, K.; Conchiero, A.; lornzo, R. A.; Piletsky, Sergey A.; Alvarez-Lorenzo, C. (Springer Verlag (Germany), 2016-08-03)
    Polymers for recovery/removal of the antimicrobial agent oxytetracycline (OTC) from aqueous media were developed with use of computational design and molecular imprinting. 2-Hydroxyethyl methacrylate, 2-acrylamide-2-methylpropane ...
  • Patterned gallium surfaces as molecular mirrors 
    Bossi, Alessandra; Rivetti, Claudio; Mangiarotti, Laura; Whitcombe, Michael J.; Turner, Anthony P. F.; Piletsky, Sergey A. (Elsevier Science B.V., Amsterdam., 2007-09-30)
    An entirely new means of printing molecular information on a planar film, involving casting nanoscale impressions of the template protein molecules in molten gallium, is presented here for the first time. The metallic ...
  • Photochemical polymerization of thiophene derivatives in aqueous solution 
    Piletsky, Sergey A.; Piletska, Elena V.; Karim, K.; Davis, Frank; Higson, Seamus P. J.; Turner, Anthony P. F. (Royal Society of Chemistry, 2004-08-20)
    A novel method of photochemical polymerization of thiophene derivatives in aqueous solution catalyzed by potassium dichromate and initiated by illumination is described.
  • Rational analysis of physico-chemical parameters affecting recognition properties of molecularly imprinted polymers 
    Guerreiro, A. (Cranfield University, 2006-05)
    Molecularly imprinted polymers (MIPs) are new type of materials with tailor made molecular recognition sites. Despite their enormous potential in separations, sensing and pharmaceutical industry, MIPs have so far failed ...
  • The rational development of molecularly imprinted polymer-based sensors for protein detection. 
    Whitcombe, Michael J.; Chianella, Iva; Larcombe, Lee; Piletsky, Sergey A.; Noble, James; Porter, Robert; Horgan, Adrian (Royal Society of Chemistry, 2011-02-22)
    The detection of specific proteins as biomarkers of disease, health status, environmental monitoring, food quality, control of fermenters and civil defence purposes means that biosensors for these targets will become ...
  • Reconfigurable microfluidic platform in ice 
    Varejka, M. (Cranfield University, 2008-04)
    Microfluidic devices are popular tools in the biotechnology industry where they provide smaller reagent requirements, high speed of analysis and the possibility for automation. The aim of the project is to make a flexible ...
  • Selection of imprinted nanoparticles by affinity chromatography 
    Guerreiro, Antonio R.; Chianella, Iva; Piletska, Elena V.; Whitcombe, Michael J.; Piletsky, Sergey A. (Elsevier Science B.V., Amsterdam., 2009-04-15)
    Soluble molecularly imprinted nanoparticles were synthesised via iniferter initiated polymerisation and separated by size via gel permeation chromatography. Subsequent fractionation of these particles by affinity chromatography ...
  • Selective vancomycin detection using optical fibre long period gratings functionalised with molecularly imprinted polymer nanoparticles 
    Korposh, Sergiy; Chianella, Iva; Guerreiro, Antonio R.; Caygill, J. S.; Piletsky, Sergey A.; James, Stephen W.; Tatam, Ralph P. (Royal Society of Chemistry, 2014-02-25)
    An optical fibre long period grating (LPG) sensor modified with molecularly imprinted polymer nanoparticles (nanoMIPs) for the specific detection of antibiotics is presented. The operation of the sensor is based on the ...
  • Solid-phase synthesis of electroactive nanoparticles of molecularly imprinted polymers. A novel platform for indirect electrochemical sensing applications 
    Mazzotta, Elisabetta; Turco, Antonio; Chianella, Iva; Guerreiro, Antonio R.; Piletsky, Sergey A.; Malitesta, Cosimino (Elsevier, 2016-01-29)
    Electroactive nanoparticles of molecularly imprinted polymers (MIP NPs) specific for a non-electroactive template (i.e., the antibiotic vancomycin) were for the first time synthesized by solid-phase synthesis adding two ...
  • The stabilisation of receptor structure in low cross-linked MIPs by an immobilised template 
    Garcinuno, Rosa M.; Chianella, Iva; Guerreiro, Antonio R.; Mijangos, Irene; Piletska, Elena V.; Whitcombe, Michael J.; Piletsky, Sergey A. (Royal Society of Chemistry, 2009-01-21)
    In molecularly imprinted polymers (MIPs) a high level of cross-linking is usually important for preserving the receptor structure. We propose here an alternative approach for stabilising binding sites, which involves the ...
  • Substitution of antibodies and receptors with molecularly imprinted polymers in enzyme-linked and fluorescent assays 
    Piletsky, Sergey A.; Piletska, Elena V.; Bossi, Alessandra; Karim, K.; Lowe, P.; Turner, Anthony P. F. (Elsevier Science B.V., Amsterdam., 2001-12-31)
    A new technique for coating microtitre plates with molecularly imprinted polymers (MIP), specific for low-molecular weight analytes (epinephrine, atrazine) and proteins is presented. Oxidative polymerization was performed ...
  • A sulfur-sulfur cross-linked polymer synthesized from a polymerizable dithiocarbamate as a source of dormant radicals 
    Garcia Con, Luis Miguel; Whitcombe, Michael J.; Piletska, Elena V.; Piletsky, Sergey A. (John Wiley & Sons, Ltd, 2010-06-01)
  • Surface imprinted beads for the recognition of human serum albumin 
    Bonini, Francesca; Piletsky, Sergey A.; Turner, Anthony P. F.; Speghini, Adolfo; Bossi, Alessandra (Elsevier Science B.V., Amsterdam., 2007-04-15)
    The synthesis of poly-aminophenylboronic acid (ABPA) imprinted beads for the recognition of the protein human serum albumin (HSA) is reported. In order to create homogeneous recognition sites, covalent immobilisation of ...
  • Surface plasmon resonance sensor for domoic acid based on grafted imprinted polymer 
    Lotierzo, M.; Henry, O. Y. F.; Piletsky, Sergey A.; Tothill, Ibtisam E.; Cullen, David C.; Kania, M.; Hock, B.; Turner, Anthony P. F. (Elsevier Science B.V., Amsterdam., 2004-09-15)
    A molecularly imprinted polymer (MIP) film for domoic acid (DA) was synthesised by direct photo-grafting onto a gold chip suitable for a surface plasmon resonance (SPR) based bioanalytical instrument system, the BIAcore ...