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Browsing Staff publications (ES) by Author "Coulon, Frederic"

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    Engineering biology applications for environmental solutions: potential and challenges
    (Springer Nature, 2025-04) Lea-Smith, David J.; Hassard, Francis; Coulon, Frederic; Partridge, Natalie; Horsfall, Louise; Parker, Kyle D. J.; Smith, Robert D. J.; McCarthy, Ronan R.; McKew, Boyd A.; Gutierrez, Tony; Kumar, Vinod; Dotro, Gabriella; Yang, Zhugen; Curtis, Thomas P.; Golyshin, Peter; Heaven, Sonia; Jefferson, Bruce; Jeffrey, Paul; Jones, Davey L.; Le Corre Pidou, Kristell; Liu, Yongqiang; Lyu, Tao; Smith, Cindy; Yakunin, Alexander; Zhang, Yue; Krasnogor, Natalio
    Engineering biology applies synthetic biology to address global environmental challenges like bioremediation, biosequestration, pollutant monitoring, and resource recovery. This perspective outlines innovations in engineering biology, its integration with other technologies (e.g., nanotechnology, IoT, AI), and commercial ventures leveraging these advancements. We also discuss commercialisation and scaling challenges, biosafety and biosecurity considerations including biocontainment strategies, social and political dimensions, and governance issues that must be addressed for successful real-world implementation. Finally, we highlight future perspectives and propose strategies to overcome existing hurdles, aiming to accelerate the adoption of engineering biology for environmental solutions.
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    Promoting global collaboration to improve bioaerosol exposure assessment and understanding of associated health impacts: outcomes from a series of workshops
    (Microbiology Society, 2025-05-15) Marczylo, Emma L.; Jackson, Simon; Bell, Christine; Andrews, Daniel; Clift, Martin J. D.; Crawford, Ian; Fejer, Gyorgy; Ferguson, Robert M. W.; Fisher, Matthew C.; Goode, Emma-Jane; Isaac, James; Kinnersley, Rob; Morrissey, Julie A.; Pozdniakova, Sofya; Viegas, Carla; Ward, Andrew; Wouters, Inge M.; Coulon, Frederic; Nasir, Zaheer A.; Douglas, Philippa
    We are surrounded, in both indoor and outdoor environments, by air containing particles of biological origin (bioaerosols). We constantly inhale them, and, depending upon their size, they deposit in different parts of our airways. Despite their ubiquitous nature and our constant exposure, bioaerosol diversity and composition of the environment are not well characterized, and we understand little about which bioaerosols we are exposed to and how this impacts our health, either positively or negatively. Indoor/Outdoor Bioaerosols Interface and Relationships Network (BioAirNet), a Clean Air Programme-funded network, has recognized the need for the bioaerosol community to reflect on the current challenges facing bioaerosol exposure assessment and the determination of the associated cellular/molecular responses driving specific health outcomes. A series of online workshops for the bioaerosol community were hosted by BioAirNet in September 2022, which aimed to bring together global expertise to discuss the current challenges impeding improved assessment of bioaerosol exposure and understanding of the downstream cellular and molecular mechanisms driving health outcomes by discussing these challenges; considering where we need to be, where we are now and how we get there. Professional facilitation was key to their success, enabling the multidisciplinary bioaerosol community to explore and address these challenges within a focused and productive environment to prioritize themes and agree on action plans for continued momentum following the workshops. These themes were as follows: (1) conceptual model; (2) stakeholder mapping; (3) knowledge transfer; (4) writing project and (5) conference-type event, collectively covering research, knowledge mobilization and networking activities. A subsequent in-person follow-up workshop was held in November 2023. It provided an opportunity to share progress on the five themes, critique what had already been done and act as a launch-pad to progress the actions further. Delegates also had the opportunity to share ongoing or upcoming work, particularly projects requiring input from others, to encourage collaborative working and sharing expertise. The use of facilitated workshops is a valuable tool for all scientific communities to collectively explore and successfully address key issues within their field.